Evidence map›Paper›PMID 35847089›Full record

ArticleFrontiers in microbiology2022

Ecological Effects of Daily Antiseptic Treatment on Microbial Composition of Saliva-Grown Microcosm Biofilms and Selection of Resistant Phenotypes.

Xiaojun Mao, Andreas Hiergeist, David L Auer, Konstantin J Scholz, Denise Muehler, Karl-Anton Hiller, Tim Maisch, Wolfgang Buchalla, Elmar Hellwig, André Gessner and 2 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in microbiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 1 pooled it
6.8field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 1 synthesis or guideline pooled it, 47 citations in OpenAlex.

  1. Pooled it
  2. Trial
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  5. Review
  6. Capsaicin inhibits cariogenicJournal of oral microbiology · 2026
    Article
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  9. Article
  10. Asiatic Acid Disrupts the Biofilm Virulence ofInternational journal of molecular sciences · 2025
    Article
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  12. Article
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  16. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Xiaojun MaoDepartment of Conservative Dentistry and Periodontology, University Hospital Regensburg, Regensburg, Germany.
Andreas HiergeistInstitute of Clinical Microbiology and Hygiene, University Hospital Regensburg, Regensburg, Germany.
David L AuerDepartment of Conservative Dentistry and Periodontology, University Hospital Regensburg, Regensburg, Germany.
Konstantin J ScholzDepartment of Conservative Dentistry and Periodontology, University Hospital Regensburg, Regensburg, Germany.
Denise MuehlerDepartment of Conservative Dentistry and Periodontology, University Hospital Regensburg, Regensburg, Germany.
Karl-Anton HillerDepartment of Conservative Dentistry and Periodontology, University Hospital Regensburg, Regensburg, Germany.
Tim MaischDepartment of Dermatology, University Hospital Regensburg, Regensburg, Germany.
Wolfgang BuchallaDepartment of Conservative Dentistry and Periodontology, University Hospital Regensburg, Regensburg, Germany.
Elmar HellwigDepartment of Operative Dentistry and Periodontology, Center for Dental Medicine, University of Freiburg, Freiburg im Breisgau, Germany.
André GessnerInstitute of Clinical Microbiology and Hygiene, University Hospital Regensburg, Regensburg, Germany.
Ali Al-AhmadDepartment of Operative Dentistry and Periodontology, Center for Dental Medicine, University of Freiburg, Freiburg im Breisgau, Germany.
Fabian CieplikDepartment of Conservative Dentistry and Periodontology, University Hospital Regensburg, Regensburg, Germany.
University Hospital Regensburg · DEUniversity of Freiburg · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Antiseptics are widely used in dental practice and included in numerous over-the-counter oral care products. However, the effects of routine antiseptic use on microbial composition of oral biofilms and on the emergence of resistant phenotypes remain unclear. Microcosm biofilms were inoculated from saliva samples of four donors and cultured in the

Indexed as

antibioticantisepticbiocidebiofilmcetylpyridinium chloridechlorhexidinedysbiosisresistance

Identifiers

PMID35847089
PMCPMC9280182
OpenAlexW4283722151

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.