Evidence map›Paper›PMID 35847083›Full record

ArticleFrontiers in microbiology2022

Alterations of Gut Microbiome and Fecal Fatty Acids in Patients With Polycystic Ovary Syndrome in Central China.

Gailing Li, Zhenguo Liu, Fang Ren, Huirong Shi, Qian Zhao, Yi Song, Xunjie Fan, Xiaojun Ma, Guijun Qin

Open access · goldAbstract read
In one paragraph

Article in Frontiers in microbiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 4 pooled it
3.1field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 4 syntheses or guidelines pooled it, 38 citations in OpenAlex.

  1. Pooled it
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  4. Pooled it
  5. Article
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  8. Review
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  13. Bacterial live therapeutics for human diseases.Molecular systems biology · 2024
    Review
  14. Article
  15. Article
  16. Article
  17. Article
  18. Gut bacteriome and mood disorders in women with PCOS.Human reproduction (Oxford, England) · 2024
    Article
  19. Fecal propionate is a signature of insulin resistance in polycystic ovary syndrome.Frontiers in cellular and infection microbiology · 2024
    Article
  20. Dysbiosis of vaginal and cervical microbiome is associated with uterine fibroids.Frontiers in cellular and infection microbiology · 2023
    Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Gailing LiGynecology Department, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Zhenguo LiuDepartment of Infectious Diseases, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Fang RenGynecology Department, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Huirong ShiGynecology Department, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Qian ZhaoGynecology Department, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Yi SongEndocrinology and Metabolic Diseases, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Xunjie FanEndocrinology and Metabolic Diseases, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Xiaojun MaEndocrinology and Metabolic Diseases, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Guijun QinEndocrinology and Metabolic Diseases, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
First Affiliated Hospital of Zhengzhou University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: The purpose of this study was to elucidate the characteristics of the gut microbiome in patients with Polycystic ovary syndrome (PCOS) and analyze the alterations of fecal fatty acid metabolism, so as to further provide the pathogenesis of PCOS. Methods: Fecal samples from the PCOS group ( Results: Serum D-lactate content in the PCOS group was higher than that in the control group. There was no significant difference in microbial α diversity and β diversity between PCOS patients and healthy controls. Peptostreptococcaceae and Bacteroidales S24-7 group existed significant differences between PCOS patients and healthy controls. Based on linear discriminant analysis selection, 14 genera including Conclusion: Specific intestinal flora fecal fatty acids and serum metabolites may mediate the occurrence and development of PCOS. PCOS patients with different body sizes have specific intestinal flora.

Indexed as

16S rRNA gene sequencingfecal fatty acidsgut microbiomepolycystic ovary syndromeuntargeted metabolomics

Identifiers

PMID35847083
PMCPMC9283120
OpenAlexW4283757939

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.