Evidence map›Paper›PMID 35846980›Full record

ArticleThe Lancet regional health. Western Pacific2022

Demonstration of a population-based HCV serosurvey in Ho Chi Minh City, Viet Nam: Establishing baseline prevalence of and continuum of care for HCV micro-elimination by 2030.

Thanh V Kim, Duc H Le, Diem V B Dao, Trang Ngoc Doan Pham, Gary W Mize, Loc T B Phan, Dan X Nguyen, Thi-Thuy-Dung Ngo, Robert G Gish, William M Lee and 7 more

Open access · goldAbstract read
In one paragraph

Article in The Lancet regional health. Western Pacific, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.0field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 6 institutions in 2 countries.

Thanh V KimPham Ngoc Thach University of Medicine, Ho Chi Minh City, Viet Nam.
Duc H LePham Ngoc Thach University of Medicine, Ho Chi Minh City, Viet Nam.
Diem V B DaoVietnam Viral Hepatitis Alliance, Reston, VA, USA.
Trang Ngoc Doan PhamVietnam Viral Hepatitis Alliance, Reston, VA, USA.
Gary W MizeVietnam Viral Hepatitis Alliance, Reston, VA, USA.
Loc T B PhanVietnam Viral Hepatitis Alliance, Reston, VA, USA.
Dan X NguyenPham Ngoc Thach University of Medicine, Ho Chi Minh City, Viet Nam.
Thi-Thuy-Dung NgoPham Ngoc Thach University of Medicine, Ho Chi Minh City, Viet Nam.
Robert G GishVietnam Viral Hepatitis Alliance, Reston, VA, USA.
William M LeeVietnam Viral Hepatitis Alliance, Reston, VA, USA.
Amy TrangVietnam Viral Hepatitis Alliance, Reston, VA, USA.
Anh N LeVietnam Viral Hepatitis Alliance, Reston, VA, USA.
Moon ChenUniversity of California at Davis, Davis, CA, USA.
Hai T PhanMedic Medical Center, Ho Chi Minh City, Viet Nam.
Binh T NguyenHo Chi Minh City Department of Health, Ho Chi Minh City, Viet Nam.
Hong K TangPham Ngoc Thach University of Medicine, Ho Chi Minh City, Viet Nam.
Doan Y DaoVietnam Viral Hepatitis Alliance, Reston, VA, USA.
Pham Ngoc Thach University of Medicine · VNJohns Hopkins University · USHepatitis B Foundation · USSouthwestern Medical Center · USUniversity Medical Center HCMC · VNUniversity of Illinois Chicago · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: A baseline of hepatitis C virus (HCV) burden and other HCV epidemiological profiles is necessary for HCV micro-elimination in Ho Chi Minh City (HCMC), Viet Nam. This study aimed to determine HCV exposure and prevalence of HCV viremia as well as the proportion of HCV testing and treatment uptake among participants. Methods: From 2019 to 2020, the probability proportionate to size sampling method was deployed to representatively invite approximately 20,000 adults (18 or older) throughout HCMC to free screening and linkage to care for HCV. Findings: In HCMC, the weighted prevalence of anti-HCV was 1·3% (95% CI, 1·1%-1·6%). Individuals born from 1945 to 1964 had the anti-HCV prevalence of 3·6% (95% CI, 3·0%-4·2%) and represented 40·4% of all HCV cases. There were wide variations in anti-HCV prevalence in HCMC, including variations between districts, risk factors, and socioeconomic statuses. A baseline HCV continuum of care for the city demonstrated that only 28·5% (85/298, 95%CI 23·4-33·7%) of persons with anti-HCV (+) were aware of their HCV status, with 77.6% (66/85, 95%CI 68·8-86·5%) diagnosing HCV incidentally, 82·7% (62/75, 95%CI 74·1-91·2%) initiating anti-HCV therapy, and 53.6% (30/56, 95%CI 40·5-66·6%) achieving HCV cures. Interpretation: There remains a considerable disease burden of HCV in HCMC of which a significant proportion was in the age group born between 1945 to 1964. Additionally, there were significant gaps in HCV awareness, screening, and access to care in the community in Viet Nam. Thus, future interventions must have pragmatic targets, be tailored to the local needs, and emphasise screening. Funding: This work was supported by investigator-sponsored research grants from Gilead Sciences Inc. (Grant No: IN-US-987-5382); Roche Diagnostic International Ltd. (Grant No. SUB-000196); and in-kind donations from Abbott Diagnostic Viet Nam; Hepatitis B Foundation; Medic Medical Center, Viet Nam; Johns Hopkins University School of Medicine's Center of Excellence for Liver Disease in Viet Nam; and the Board of Directors, Viet Nam Viral Hepatitis Alliance (V-VHA).

Indexed as

2030Access to careFrameworkHCV baseline linkage to careHCV screeningHepatitis C virusHo Chi Minh City (HCMC)Micro-eliminationNational eliminationViet Nam

Identifiers

PMID35846980
PMCPMC9283666
OpenAlexW4284974811

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.