Evidence map›Paper›PMID 35846763›Full record

ArticleFrontiers in cellular and infection microbiology2022

Antibacterial and Antibiofilm Potency of XF Drugs, Impact of Photodynamic Activation and Synergy With Antibiotics.

Emma Louise Board-Davies, William Rhys-Williams, Daniel Hynes, David Williams, Damian Joseph John Farnell, William Love

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cellular and infection microbiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.8field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Carbon Dots in Photodynamic/Photothermal Antimicrobial Therapy.Nanomaterials (Basel, Switzerland) · 2024
    Review
  3. Review
  4. Biofilm and wound healing: from bench to bedside.European journal of medical research · 2023
    Review
  5. Antimicrobial effects of XF drugs againstFrontiers in fungal biology · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Emma Louise Board-DaviesSchool of Dentistry, Cardiff University, Cardiff, United Kingdom.
William Rhys-WilliamsDestiny Pharma plc, Brighton, United Kingdom.
Daniel HynesDestiny Pharma plc, Brighton, United Kingdom.
David WilliamsSchool of Dentistry, Cardiff University, Cardiff, United Kingdom.
Damian Joseph John FarnellSchool of Dentistry, Cardiff University, Cardiff, United Kingdom.
William LoveDestiny Pharma plc, Brighton, United Kingdom.
Cardiff University · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

With increasing incidence of antimicrobial resistance, there is an urgent need for novel and effective antibacterials. Destiny Pharma plc have developed a series of porphyrin-based XF drugs, some with dual mechanisms of antibacterial action. An innate mechanism acts through binding to the outer bacterial membrane and a separate, light-activated, photodynamic (PD) mechanism, acts

Indexed as

Anti-Bacterial AgentsMethicillin-Resistant Staphylococcus aureusBiofilmsMicrobial Sensitivity TestsPseudomonas aeruginosaAnti-Bacterial Agentsantibacterialantimicrobial resistancebiofilmsphotodynamic therapyXF drugs

Identifiers

PMID35846763
PMCPMC9279914
OpenAlexW4283762670

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.