Evidence map›Paper›PMID 35846563›Full record

ArticleFrontiers in cellular neuroscience2022

Exosomes Derived From Umbilical Cord Mesenchymal Stem Cells Treat Cutaneous Nerve Damage and Promote Wound Healing.

Ziying Zhu, Xiaona Zhang, Haojie Hao, Heran Xu, Jun Shu, Qian Hou, Min Wang

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in cellular neuroscience, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed, 1 pooled it
6.2field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed, 1 synthesis or guideline pooled it, 63 citations in OpenAlex.

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  3. [Research advances on the application of skin appendage organoids in wound repair].Zhonghua shao shang yu chuang mian xiu fu za zhi · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Ziying ZhuCollege of Chemistry and Materials Engineering, Beijing Technology and Business University, Beijing, China.
Xiaona ZhangCollege of Chemistry and Materials Engineering, Beijing Technology and Business University, Beijing, China.
Haojie HaoThe First Medical Center, Chinese People's Liberation Army General Hospital, Beijing, China.
Heran XuCollege of Chemistry and Materials Engineering, Beijing Technology and Business University, Beijing, China.
Jun ShuThe First Medical Center, Chinese People's Liberation Army General Hospital, Beijing, China.
Qian HouThe First Medical Center, Chinese People's Liberation Army General Hospital, Beijing, China.
Min WangCollege of Chemistry and Materials Engineering, Beijing Technology and Business University, Beijing, China.
Beijing Technology and Business University · CNChinese People's Liberation Army · CNChinese PLA General Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Wound repair is a key step in the treatment of skin injury caused by burn, surgery, and trauma. Various stem cells have been proven to promote wound healing and skin regeneration as candidate seed cells. Therefore, exosomes derived from stem cells are emerging as a promising method for wound repair. However, the mechanism by which exosomes promote wound repair is still unclear. In this study, we reported that exosomes derived from umbilical cord mesenchymal stem cells (UC-MSCs) promote wound healing and skin regeneration by treating cutaneous nerve damage. The results revealed that UC-MSCs exosomes (UC-MSC-Exo) promote the growth and migration of dermal fibroblast cells. In

Indexed as

cutaneous nerve regenerationexosomenerve growth factorregenerationumbilical cord mesenchymal stem cellswound repair

Identifiers

PMID35846563
PMCPMC9279568
OpenAlexW4283731781

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.