Evidence map›Paper›PMID 35846143›Full record

ArticleFrontiers in genetics2022

Histone Demethylase AMX-1 Regulates Fertility in a p53/CEP-1 Dependent Manner.

Xiaojing Ren, Sisi Tian, Qinghao Meng, Hyun-Min Kim

Open access · goldAbstract read
In one paragraph

Article in Frontiers in genetics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.7field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Therapeutic Potential ofPharmaceuticals (Basel, Switzerland) · 2025
    Article
  5. Review
  6. Exploring the Impact ofNutrients · 2023
    Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Xiaojing RenSchool of Pharmaceutical Science and Technology, Tianjin University, Tianjin, China.
Sisi TianSchool of Pharmaceutical Science and Technology, Tianjin University, Tianjin, China.
Qinghao MengSchool of Pharmaceutical Science and Technology, Tianjin University, Tianjin, China.
Hyun-Min KimSchool of Pharmaceutical Science and Technology, Tianjin University, Tianjin, China.
Duke Kunshan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Histone methylation shapes the epigenetic configuration and adjusts multiple fundamental nuclear processes, including transcription, cell cycle control and DNA repair. The absence of histone demethylase LSD1/SPR-5 leads to progressive fertility defects as well as a reduction in brood size. Similarly,

Indexed as

CEP-1fertilityhistone methylationLSD2p53Piwisterilitytransposon

Identifiers

PMID35846143
PMCPMC9280695
OpenAlexW4283747892

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.