Evidence map›Paper›PMID 35846099›Full record

ArticleEJHaem2021

Ruxolitinib is effective in the treatment of a patient with refractory T-ALL.

Sonia Jaramillo, Hannah Hennemann, Peter Horak, Veronica Teleanu, Christoph E Heilig, Barbara Hutter, Albrecht Stenzinger, Hanno Glimm, Benjamin Goeppert, Carsten Müller-Tidow and 3 more

Open access · diamondAbstract read
In one paragraph

Article in EJHaem, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.1field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 1 country.

Sonia JaramilloDepartment of Hematology Oncology, and Rheumatology Heidelberg University Hospital University of Heidelberg Heidelberg Germany.ORCID https://orcid.org/0000-0002-2397-3070
Hannah HennemannDepartment of Hematology Oncology, and Rheumatology Heidelberg University Hospital University of Heidelberg Heidelberg Germany.
Peter HorakDivision of Translational Medical Oncology National Center for Tumor Diseases (NCT) Heidelberg, and German Cancer Research Center (DKFZ) Heidelberg Germany.
Veronica TeleanuDivision of Translational Medical Oncology National Center for Tumor Diseases (NCT) Heidelberg, and German Cancer Research Center (DKFZ) Heidelberg Germany.
Christoph E HeiligDivision of Translational Medical Oncology National Center for Tumor Diseases (NCT) Heidelberg, and German Cancer Research Center (DKFZ) Heidelberg Germany.
Barbara HutterComputational Oncology, Molecular Diagnostics Program NCT and DKFZ Heidelberg Germany.
Albrecht StenzingerInstitute of Pathology University of Heidelberg Heidelberg Germany.
Hanno GlimmDepartment of Translational Medical Oncology NCT Dresden, Dresden, and DKFZ Heidelberg Germany.
Benjamin GoeppertInstitute of Pathology University of Heidelberg Heidelberg Germany.
Carsten Müller-TidowDepartment of Hematology Oncology, and Rheumatology Heidelberg University Hospital University of Heidelberg Heidelberg Germany.
Stefan FröhlingDivision of Translational Medical Oncology National Center for Tumor Diseases (NCT) Heidelberg, and German Cancer Research Center (DKFZ) Heidelberg Germany.
Stefan SchönlandDepartment of Hematology Oncology, and Rheumatology Heidelberg University Hospital University of Heidelberg Heidelberg Germany.
Richard F SchlenkDepartment of Hematology Oncology, and Rheumatology Heidelberg University Hospital University of Heidelberg Heidelberg Germany.ORCID https://orcid.org/0000-0003-2215-2059
Heidelberg University · DEGerman Cancer Research Center · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

T-cell acute lymphoblastic leukemia (T-ALL) is a rare, aggressive T-cell malignancy. Chemotherapy alone cures only 25-45% of the cases, thus, novel treatment agents and strategies are urgently needed. We assessed the efficacy of ruxolitinib in a patient with a cutaneous relapse after allogeneic blood cell transplantation of a refractory T-ALL with a Janus kinase 3 (

Identifiers

PMID35846099
PMCPMC9175749
OpenAlexW3110584264

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.