Evidence map›Paper›PMID 35846087›Full record

ArticleEJHaem2021

Adult T cell leukaemia/lymphoma (ATL) in pregnancy: A UK case series.

Leila Motedayen Aval, Mary Boullier, Hermione Lyall, Graham P Collins, Robert Ayto, Dominic F Kelly, Richard S Tedder, Simon B Drysdale, Graham P Taylor, Lucy B Cook

Open access · diamondAbstract read
In one paragraph

Article in EJHaem, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.5field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 9 citations in OpenAlex.

  1. Review
  2. How Can We Prevent Mother-to-Child Transmission of HTLV-1?International journal of molecular sciences · 2023
    Review
  3. Article
  4. Article
  5. Review
  6. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 6 institutions in 1 country.

Leila Motedayen AvalSection of Virology, Imperial College London UK.
Mary BoullierDepartment of Paediatrics St George's University Hospitals NHS Foundation Trust London UK.
Hermione LyallDepartment of Paediatric Infectious Diseases Imperial College Healthcare NHS Trust London UK.
Graham P CollinsDepartment of Haematology Oxford University Hospitals NHS Foundation Trust Oxford UK.
Robert AytoDepartment of Haematology Portsmouth Hospitals NHS Trust Hampshire UK.
Dominic F KellyOxford Vaccine Group Department of Paediatrics University of Oxford Oxford UK.
Richard S TedderSection of Virology, Imperial College London UK.
Simon B DrysdaleDepartment of Paediatrics St George's University Hospitals NHS Foundation Trust London UK.
Graham P TaylorSection of Virology, Imperial College London UK.
Lucy B CookSection of Virology, Imperial College London UK.ORCID https://orcid.org/0000-0002-8234-5090
Imperial College Healthcare NHS Trust · GBNIHR Imperial Biomedical Research Centre · GBSt George’s University Hospitals NHS Foundation Trust · GBOxford University Hospitals NHS Trust · GBPortsmouth Hospitals NHS Trust · GBUniversity of Oxford · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Chronic infection with human T-cell lymphotropic virus type-1 (HTLV-1) may result in aggressive adult T-cell leukaemia/lymphoma (ATL) in 4-6% carriers. The majority of this risk arises in carriers infected during infancy, and so each infant has ∼25% lifetime risk. Other risk factors include a family history of ATL. Antenatal HTLV-1 screening is not undertaken in the UK. Methods: Here we describe four cases of ATL diagnosed during pregnancy and describe strategies to minimise HTLV-1 transmission to neonates. Results/conclusion: These cases highlight undiagnosed HTLV-1 in pregnancy which allows ongoing mother to child vertical transmission and risk of future ATL. We recommend the UK National Screening Committee incorporate HTLV-1 serology into antenatal screening.

Indexed as

antiretroviralsATLHTLV‐1pregnancyscreening

Identifiers

PMID35846087
PMCPMC9175930
OpenAlexW3109717099

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.