Evidence map›Paper›PMID 35846061›Full record

ArticleEJHaem2022

Haematological malignancies in relatives of patients affected with myeloproliferative neoplasms.

Daniele Vanni, Oscar Borsani, Yasuhito Nannya, Emanuela Sant'Antonio, Chiara Trotti, Ilaria Carola Casetti, Daniela Pietra, Anna Gallì, Silvia Zibellini, Virginia Valeria Ferretti and 4 more

Open access · diamondAbstract read
In one paragraph

Article in EJHaem, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 53% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 6 institutions in 3 countries.

Daniele VanniDepartment of Molecular Medicine University of Pavia Pavia Italy.
Oscar BorsaniDepartment of Molecular Medicine University of Pavia Pavia Italy.ORCID https://orcid.org/0000-0001-7805-7806
Yasuhito NannyaDepartment of Pathology and Tumor Biology Kyoto University Kyoto Japan.
Emanuela Sant'AntonioDivision of Haematology Azienda USL Toscana Nord Ovest Lucca Italy.
Chiara TrottiDepartment of Molecular Medicine University of Pavia Pavia Italy.
Ilaria Carola CasettiDepartment of Molecular Medicine University of Pavia Pavia Italy.
Daniela PietraDivision of Haematology Fondazione Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Policlinico San Matteo Pavia Italy.
Anna GallìDivision of Haematology Fondazione Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Policlinico San Matteo Pavia Italy.
Silvia ZibelliniDivision of Haematology Fondazione Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Policlinico San Matteo Pavia Italy.
Virginia Valeria FerrettiService of Clinical Epidemiology and Biostatistics Fondazione Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Policlinico San Matteo Pavia Italy.
Luca MalcovatiDepartment of Molecular Medicine University of Pavia Pavia Italy.
Seishi OgawaDepartment of Pathology and Tumor Biology Kyoto University Kyoto Japan.
Luca ArcainiDepartment of Molecular Medicine University of Pavia Pavia Italy.
Elisa RumiDepartment of Molecular Medicine University of Pavia Pavia Italy.ORCID https://orcid.org/0000-0002-7572-9504
University of Pavia · ITPoliclinico San Matteo Fondazione · ITAzienda Usl Toscana Centro · ITIstituti di Ricovero e Cura a Carattere Scientifico · ITKyoto University · JPTokyo Medical University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In a cohort of 3131 patients with myeloproliferative neoplasms (MPNs), we identified 200 patients (6.4%) who reported a second case of haematological malignancies (HM) in first- or second-degree relatives. The occurrence of a second HM in the family was not influenced by MPN subtype, sex or driver mutation, while it was associated with age at MPN diagnosis: 8.5% of patients diagnosed with MPN younger than 45 years had a second relative affected with HM compared to 5.5% of those diagnosed at the age of 45 years or older (

Indexed as

familialmalignanciesmyeloproliferativerelatives

Identifiers

PMID35846061
PMCPMC9176120
OpenAlexW4220749662

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.