Evidence map›Paper›PMID 35846032›Full record

ArticleEJHaem2022

Clinical impact of central nervous system-directed therapies on intravascular large B-cell lymphoma: A single institution's experience.

Hiromichi Takahashi, Haruna Nishimaki, Yoko Nakanishi, Takashi Hamada, Masaru Nakagawa, Kazuhide Iizuka, Yoshihito Uchino, Noriyoshi Iriyama, Katsuhiro Miura, Tomohiro Nakayama and 3 more

Open access · diamondAbstract read
In one paragraph

Article in EJHaem, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 1 institution in 1 country.

Hiromichi TakahashiDepartment of Medicine Division of Hematology and Rheumatology Nihon University School of Medicine Tokyo Japan.
Haruna NishimakiDepartment of Pathology and Microbiology Division of Oncologic Pathology Nihon University School of Medicine Tokyo Japan.
Yoko NakanishiDepartment of Pathology and Microbiology Division of Oncologic Pathology Nihon University School of Medicine Tokyo Japan.
Takashi HamadaDepartment of Medicine Division of Hematology and Rheumatology Nihon University School of Medicine Tokyo Japan.
Masaru NakagawaDepartment of Medicine Division of Hematology and Rheumatology Nihon University School of Medicine Tokyo Japan.
Kazuhide IizukaDepartment of Medicine Division of Hematology and Rheumatology Nihon University School of Medicine Tokyo Japan.
Yoshihito UchinoDepartment of Medicine Division of Hematology and Rheumatology Nihon University School of Medicine Tokyo Japan.
Noriyoshi IriyamaDepartment of Medicine Division of Hematology and Rheumatology Nihon University School of Medicine Tokyo Japan.
Katsuhiro MiuraDepartment of Medicine Division of Hematology and Rheumatology Nihon University School of Medicine Tokyo Japan.ORCID https://orcid.org/0000-0002-1538-3804
Tomohiro NakayamaDepartment of Pathology and Microbiology Division of Laboratory Medicine Nihon University School of Medicine Tokyo Japan.
Shinobu MasudaDepartment of Pathology and Microbiology Division of Oncologic Pathology Nihon University School of Medicine Tokyo Japan.
Yoshihiro HattaDepartment of Medicine Division of Hematology and Rheumatology Nihon University School of Medicine Tokyo Japan.
Hideki NakamuraDepartment of Medicine Division of Hematology and Rheumatology Nihon University School of Medicine Tokyo Japan.
Nihon University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Intravascular large B-cell lymphoma (IVLBCL) is a rare subtype of B-cell lymphoma characterized by aggressive disease progression with a high incidence of central nervous system (CNS) involvement. We retrospectively analyzed 16 patients with de novo IVLBCL treated at our hospital between 2004 and 2018 with either standard therapy plus CNS-directed therapy or standard therapy alone. CNS-directed therapy was associated with a significantly better 2-year CNS-free survival (100% vs. 63%,

Indexed as

central nervous systemhigh‐dose chemotherapyintravascular large B‐cell lymphomamethotrexateprogrammed death‐ligand 1

Identifiers

PMID35846032
PMCPMC9176124
OpenAlexW4210384796

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.