Evidence map›Paper›PMID 35845955›Full record

ReviewBioMed research international2022

Artificial Intelligence-Based Data-Driven Strategy to Accelerate Research, Development, and Clinical Trials of COVID Vaccine.

Ashwani Sharma, Tarun Virmani, Vipluv Pathak, Anjali Sharma, Kamla Pathak, Girish Kumar, Devender Pathak

Abstract readReview
In one paragraph

Review in BioMed research international, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Review
  4. Review
  5. Article
  6. Review
  7. Review
  8. Review
  9. Review
  10. New advances in oral microbiology and tumor research.World journal of clinical oncology · 2025
    Review
  11. Review
  12. Article
  13. Review
  14. Review
  15. Review
  16. Review
  17. Review
  18. Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Ashwani SharmaSchool of Pharmaceutical Sciences, MVN University, Haryana 121102, India.ORCID https://orcid.org/0000-0001-9399-0856
Tarun VirmaniSchool of Pharmaceutical Sciences, MVN University, Haryana 121102, India.ORCID https://orcid.org/0000-0002-1615-5213
Vipluv PathakGL Bajaj Institute of Technology and Management, Greater Noida, Uttar Pradesh, India.ORCID https://orcid.org/0000-0002-9690-1430
Anjali SharmaFreelancer, Pharmacovigilance Expert, India.ORCID https://orcid.org/0000-0002-7881-1650
Kamla PathakUttar Pradesh University of Medical Sciences, Etawah, Uttar Pradesh 206001, India.ORCID https://orcid.org/0000-0001-9074-9792
Girish KumarSchool of Pharmaceutical Sciences, MVN University, Haryana 121102, India.ORCID https://orcid.org/0000-0002-2917-3277
Devender PathakRajiv Academy for Pharmacy, NH. #2, Mathura Delhi Road P.O, Chhatikara, Mathura, Uttar Pradesh 281001, India.ORCID https://orcid.org/0000-0002-1862-1484

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The global COVID-19 (coronavirus disease 2019) pandemic, which was caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has resulted in a significant loss of human life around the world. The SARS-CoV-2 has caused significant problems to medical systems and healthcare facilities due to its unexpected global expansion. Despite all of the efforts, developing effective treatments, diagnostic techniques, and vaccinations for this unique virus is a top priority and takes a long time. However, the foremost step in vaccine development is to identify possible antigens for a vaccine. The traditional method was time taking, but after the breakthrough technology of reverse vaccinology (RV) was introduced in 2000, it drastically lowers the time needed to detect antigens ranging from 5-15 years to 1-2 years. The different RV tools work based on machine learning (ML) and artificial intelligence (AI). Models based on AI and ML have shown promising solutions in accelerating the discovery and optimization of new antivirals or effective vaccine candidates. In the present scenario, AI has been extensively used for drug and vaccine research against SARS-COV-2 therapy discovery. This is more useful for the identification of potential existing drugs with inhibitory human coronavirus by using different datasets. The AI tools and computational approaches have led to speedy research and the development of a vaccine to fight against the coronavirus. Therefore, this paper suggests the role of artificial intelligence in the field of clinical trials of vaccines and clinical practices using different tools.

Indexed as

COVID-19VaccinesArtificial IntelligenceClinical Trials as TopicCOVID-19 VaccinesHumansSARS-CoV-2COVID-19 VaccinesVaccines

Identifiers

PMID35845955
PMCPMC9279074

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.