Evidence map›Paper›PMID 35845938›Full record

ArticleBioMed research international2022

Female Colon Cancer Metastasis Pattern and Prognosis: A SEER-Based Study.

Yurong Liu, Rongbin Kang, Huida Zheng, Pengcheng Wang, Weixin Jiang, Bin Xiong, Jintao Chen, Jianhua Xu

RetractedOpen access · hybridAbstract readRetracted Publication
In one paragraph

Article in BioMed research international, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.7field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 5 citations in OpenAlex.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Yurong LiuDepartment of Gastrointestinal Surgery, The Second Affiliated Hospital of Fujian Medical University, Quanzhou, China.ORCID https://orcid.org/0000-0001-7280-1745
Rongbin KangDepartment of Gastric Surgery, Fujian Medical University Union Hospital, Fuzhou, China.
Huida ZhengDepartment of Gastrointestinal Surgery, The Second Affiliated Hospital of Fujian Medical University, Quanzhou, China.
Pengcheng WangDepartment of Gastrointestinal Surgery, The Second Affiliated Hospital of Fujian Medical University, Quanzhou, China.
Weixin JiangDepartment of Gastrointestinal Surgery, The Second Affiliated Hospital of Fujian Medical University, Quanzhou, China.
Bin XiongDepartment of Gastrointestinal Surgery, The Second Affiliated Hospital of Fujian Medical University, Quanzhou, China.
Jintao ChenDepartment of Endocrinology, The Affiliated Hospital of Qingdao University, Qingdao, China.
Jianhua XuDepartment of Gastrointestinal Surgery, The Second Affiliated Hospital of Fujian Medical University, Quanzhou, China.ORCID https://orcid.org/0000-0001-5147-292X
Fujian Medical University · CNQingdao University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The purpose of this study was to compare the metastatic pattern and prognosis of female colon cancer (FCC) to that of male colon cancer (MCC) to ascertain the independent factors impacting the prognosis of patients with FCC. The data of the present study population were retrieved from the Surveillance, Epidemiology, and End Results (SEER) database. Descriptive analysis, the Kaplan-Meier method, and the Cox regression were used to evaluated FCC characteristics and factors associated with prognosis. There were 56,442 patients diagnosed with FCC, of whom 8,817 had distant metastases. Compared to patients with nonmetastatic FCC, a greater proportion of metastatic FCC patients was less than 60 years of age, black race, and grade III-IV. The primary sites were mainly located on the left side and have more possibility to receive chemotherapy and radiotherapy. Compared to metastatic MCC, a higher proportion of metastatic FCC patients ranged over 60 years of age, black race, treated without chemotherapy, and insurance, while the primary site was located on the right side. Liver and lung were the two most common sites of solitary metastases in CC, and among patients with solitary metastases in CC, patients who had lung metastases had a better prognosis than those who developed other types of metastasizes. Patients with FCC with metastases of the liver had a worse prognosis than their MCC counterparts. Cox multivariate regression analysis showed that the risk ratio was higher in metastatic FCC patients compared to those without metastases. We report the survival comparison of metastatic FCC with nonmetastatic FCC through the SEER database. Our results suggest that it has unique clinicopathological features and differs from metastatic MCC. Furthermore, patients with liver metastatic FCC have a worse prognosis than those with MCC. Emphasis on screening for colon cancer in women and additional clinical care should be paid for, especially for patients with FCC with metastatic liver cancer.

Indexed as

Colonic NeoplasmsLiver NeoplasmsRectal NeoplasmsAgedFemaleHumansKaplan-Meier EstimateMaleMiddle AgedNeoplasm MetastasisNeoplasm StagingPrognosisSEER Program

Identifiers

PMID35845938
PMCPMC9283037
OpenAlexW4284885270

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.