Evidence map›Paper›PMID 35845925›Full record

ArticleBioMed research international2022

Effect of Thymoquinone on Renal Damage Induced by Hyperlipidemia in LDL Receptor-Deficient (LDL-R

Wanjing Li, Hujin Zhang, Lei Zhang, Taipeng Zhang, Hui Ding

Open access · hybridAbstract read
In one paragraph

Article in BioMed research international, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.5field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Effect of Doum (Frontiers in nutrition · 2026
    Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Wanjing LiDepartment of Cardiology, Xi'an No. 3 Hospital, The Affiliated Hospital of Northwest University, Xi'an, Shaanxi 710018, China.ORCID https://orcid.org/0000-0001-7550-1510
Hujin ZhangDepartment of Neurosurgery, Xi'an Central Hospital, Xi'an, Shaanxi 710003, China.ORCID https://orcid.org/0000-0001-8522-6196
Lei ZhangDepartment of Cardiology, Xi'an No. 3 Hospital, The Affiliated Hospital of Northwest University, Xi'an, Shaanxi 710018, China.ORCID https://orcid.org/0000-0002-1389-1960
Taipeng ZhangUniversity of South California, 1441 Eastlake Ave., Rm. 7415, Los Angeles, CA 90033, USA.ORCID https://orcid.org/0000-0002-5722-713X
Hui DingDepartment of Cardiology, Xi'an No. 3 Hospital, The Affiliated Hospital of Northwest University, Xi'an, Shaanxi 710018, China.ORCID https://orcid.org/0000-0002-1602-9487
Northwest University · CNUniversity of Southern California · USXian Central Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hyperlipidemia is a well-established risk factor for kidney injury, which can lead to chronic kidney disease (CKD). Thymoquinone (TQ) is one of the most active ingredients in Nigella sativa seeds. It has various beneficial properties, including antioxidant and anti-inflammatory activities. TQ also exerts positive effects on doxorubicin- (DOX-) induced nephropathy and ischemia-reperfusion-induced kidney injury in rats. Therefore, in this study, we investigated the possible protective effects of TQ against kidney injury in low-density lipoprotein receptor-deficient (LDL-R

Indexed as

HyperlipidemiasKidney DiseasesReperfusion InjuryAnimalsBenzoquinonesCholesterol, LDLCytokinesDoxorubicinKidneyMaleMiceOxidative StressRatsReceptors, LDLBenzoquinonesCholesterol, LDLCytokinesDoxorubicinReceptors, LDLthymoquinone

Identifiers

PMID35845925
PMCPMC9279052
OpenAlexW4285818802

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.