Evidence map›Paper›PMID 35845579›Full record

ReviewEvidence-based complementary and alternative medicine : eCAM2022

Efficacy and Safety of Shuganjieyu Capsule Alone or in Combination with Other Antidepressants in the Treatment of Postpartum Depression: A Meta-Analysis.

Lingning Wang, Yan Fan, Jiangmen He, Heng Liu, Feng Chen, Hongying Dan, Juan Zhao, Jiao Zhang, Tao Wang, Xinru Liu

Open access · hybridAbstract readReview
In one paragraph

Review in Evidence-based complementary and alternative medicine : eCAM, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
0.6field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 4 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Study on subtyping and Traditional Chinese Medicine treatment of depression based on machine learning and text mining.Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan · 2025
    Article
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Lingning WangDepartment of Obstetrics and Gynecology Clinics, West China Second University Hospital, Sichuan University, Chengdu 610041, China.
Yan FanDepartment of Obstetrics and Gynecology Clinics, West China Second University Hospital, Sichuan University, Chengdu 610041, China.
Jiangmen HeDepartment of Obstetrics and Gynecology Clinics, West China Second University Hospital, Sichuan University, Chengdu 610041, China.
Heng LiuDepartment of Obstetrics and Gynecology Clinics, West China Second University Hospital, Sichuan University, Chengdu 610041, China.
Feng ChenDepartment of Obstetrics and Gynecology Clinics, West China Second University Hospital, Sichuan University, Chengdu 610041, China.
Hongying DanDepartment of Obstetrics and Gynecology Clinics, West China Second University Hospital, Sichuan University, Chengdu 610041, China.
Juan ZhaoDepartment of Obstetrics and Gynecology Clinics, West China Second University Hospital, Sichuan University, Chengdu 610041, China.
Jiao ZhangDepartment of Obstetrics and Gynecology Clinics, West China Second University Hospital, Sichuan University, Chengdu 610041, China.
Tao WangKey Laboratory of Birth Defects and Related Diseases of Women and Children (Sichuan University), Ministry of Education, Chengdu 610041, China.ORCID https://orcid.org/0000-0002-8477-4542
Xinru LiuDepartment of Obstetrics and Gynecology Clinics, West China Second University Hospital, Sichuan University, Chengdu 610041, China.ORCID https://orcid.org/0000-0002-8875-0222
Sichuan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To evaluate the efficacy and safety of Shuganjieyu capsule alone or in combination with other antidepressants in the treatment of postpartum depression. Methods: Related control and randomized studies till August 1, 2021, were retrieved from the following databases: PubMed, Cochrane, CNKI, CMB, Wan-Fang, and VIP. Outcomes included HAMD reduction from baseline, response rate, and adverse events rate. Review Manager 5.3 was used in the present meta-analysis. Results: 16 studies including 1409 participants were included in the present study. In comparison of single Shuganjieyu capsule versus regular antidepressant, 8, 6, and 4-week HAMD reduction of the Shuganjieyu group were significantly higher (8-week MD: 3.1 (1.54, 4.66), Conclusion: Compared with regular antidepressants, single Shuganjieyu capsule has similar efficacy and better safety profile; when Shuganjieyu capsule is combined with regular antidepressants, the efficacy is improved significantly without increasing adverse events. Therefore, Shuganjieyu capsule was effective and safe for postpartum, making it worth further investigation and popularization.

Identifiers

PMID35845579
PMCPMC9283059
OpenAlexW4284896449

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.