Evidence map›Paper›PMID 35845537›Full record

ArticleAnnals of translational medicine2022

Two case reports of non-small cell lung cancer patients harboring acquired

Zizheng Song, Guanying Ren, Ling Hu, Xiaolei Wang, Jin Song, Youchao Jia, Guofa Zhao, Aimin Zang, Haiwei Du, Ying Sun and 1 more

Open access · diamondAbstract readCase Reports
In one paragraph

Article in Annals of translational medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.4field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 10 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Zizheng Song *Department of Medical Oncology, Affiliated Hospital of Hebei University, Baoding, China.
Guanying Ren *Department of Medical Oncology, Affiliated Hospital of Hebei University, Baoding, China.
Ling HuDepartment of Medical Oncology, Affiliated Hospital of Hebei University, Baoding, China.
Xiaolei WangDepartment of Medical Oncology, Affiliated Hospital of Hebei University, Baoding, China.
Jin SongDepartment of Medical Oncology, Affiliated Hospital of Hebei University, Baoding, China.
Youchao JiaDepartment of Medical Oncology, Affiliated Hospital of Hebei University, Baoding, China.
Guofa ZhaoDepartment of Medical Oncology, Affiliated Hospital of Hebei University, Baoding, China.
Aimin ZangDepartment of Medical Oncology, Affiliated Hospital of Hebei University, Baoding, China.
Haiwei DuDepartment of Data Science, Burning Rock Biotech, Guangzhou, China.
Ying SunDepartment of Medicine, Burning Rock Biotech, Guangzhou, China.
Xiaopeng ZhaoDepartment of Thoracic surgery, The Fourth Hospital of Hebei Medical University, Shijiazhuang, China.
Affiliated Hospital of Hebei University · CNBurning Rock Biotech (China) · CNHebei Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Acquired resistance is inevitable in non-small cell lung cancer (NSCLC) patients treated with epidermal growth factor receptor tyrosine kinase inhibitors (EGFR-TKIs). The emergence of Case Description: Herein, we reported two cases of Conclusions: Our study provides the first clinical evidence that ICIs combined with platinum-based doublet chemotherapy may be effective treatment options for overcoming resistance mediated by

Indexed as

case reportEpidermal growth factor receptor (EGFR)immune checkpoint inhibitor (ICI)non-small cell lung cancer (NSCLC)T790M-cis-C797S

Identifiers

PMID35845537
PMCPMC9279785
OpenAlexW4283722016

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.