ReviewFrontiers in bioengineering and biotechnology2022
Spatio-Temporal Modification of Lignin Biosynthesis in Plants: A Promising Strategy for Lignocellulose Improvement and Lignin Valorization.
Review in Frontiers in bioengineering and biotechnology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
16 citing papers in PubMed, 38 citations in OpenAlex.
- Overcoming Biomass Recalcitrance Heterogeneity Using a Surfactant-Based CTAB/LA/CuApplied biochemistry and biotechnology · 2026Article
- The genome of Cynanchum thesioides (Freyn) K. Schum provides insights into its systematics and candidate genes potentially associated with drought tolerance as a xerophyte.BMC plant biology · 2026Article
- Elucidating the mechanistic link: how silicon enhances lodging resistance in oat via targeted regulation of lignin biosynthesis in the second stem internode.Frontiers in plant science · 2026Article
- Mechanisms of acclimation regulation and stress response to UV-B inFrontiers in plant science · 2026Article
- Advances in lignocellulosic feedstocks for bioenergy and bioproducts.Nature communications · 2025Review
- Genome-wide analysis of the COMT gene family inFrontiers in plant science · 2025Article
- Genome-wide identification and expression analysis ofFrontiers in plant science · 2025Article
- Metabolic engineering ofPlant biotechnology (Tokyo, Japan) · 2024Article
- Genome-wide identification of thePeerJ · 2024Article
- Grass lignin: biosynthesis, biological roles, and industrial applications.Frontiers in plant science · 2024Review
- An evaluation of Astragali Radix with different growth patterns and years, based on a new multidimensional comparison method.Frontiers in plant science · 2024Article
- Polymeric Materials Obtained by Extrusion and Injection Molding from Lignocellulosic Agroindustrial Biomass.Polymers · 2023Review
- Ergosterol and Its Metabolites Induce Ligninolytic Activity in the Lignin-Degrading FungusJournal of fungi (Basel, Switzerland) · 2023Article
- Mass spectrometry imaging and single-cell transcriptional profiling reveal the tissue-specific regulation of bioactive ingredient biosynthesis in Taxus leaves.Plant communications · 2023Article
- A large-scale forward genetic screen for maize mutants with altered lignocellulosic properties.Frontiers in plant science · 2023Article
- OsGLP participates in the regulation of lignin synthesis and deposition in rice against copper and cadmium toxicity.Frontiers in plant science · 2022Article
Corrections and comments
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Authors and funding
8 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Lignin is essential for plant growth, structural integrity, biotic/abiotic stress resistance, and water transport. Besides, lignin constitutes 10-30% of lignocellulosic biomass and is difficult to utilize for biofuel production. Over the past few decades, extensive research has uncovered numerous metabolic pathways and genes involved in lignin biosynthesis, several of which have been highlighted as the primary targets for genetic manipulation. However, direct manipulation of lignin biosynthesis is often associated with unexpected abnormalities in plant growth and development for unknown causes, thus limiting the usefulness of genetic engineering for biomass production and utilization. Recent advances in understanding the complex regulatory mechanisms of lignin biosynthesis have revealed new avenues for spatial and temporal modification of lignin in lignocellulosic plants that avoid growth abnormalities. This review explores recent work on utilizing specific transcriptional regulators to modify lignin biosynthesis at both tissue and cellular levels, focusing on using specific promoters paired with functional or regulatory genes to precisely control lignin synthesis and achieve biomass production with desired properties. Further advances in designing more appropriate promoters and other regulators will increase our capacity to modulate lignin content and structure in plants, thus setting the stage for high-value utilization of lignin in the future.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.