Evidence map›Paper›PMID 35845283›Full record

ArticleEJHaem2021

Sirolimus versus cyclosporine in haploidentical stem cell transplantation with posttransplant cyclophosphamide and mycophenolate mofetil as graft-versus-host disease prophylaxis.

Rafael Hernani, José Luis Piñana, Ariadna Pérez, Abdiel Quintero, Juan Montoro, Juan C Hernández-Boluda, Carlos Carretero, Aitana Balaguer-Roselló, Manuel Guerreiro, Ignacio Lorenzo and 6 more

Open access · diamondAbstract read
In one paragraph

Article in EJHaem, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 4 institutions in 1 country.

Rafael HernaniDepartment of Haematology Hospital Clínico Universitario Institute for Research INCLIVA Valencia Spain.ORCID https://orcid.org/0000-0003-1043-8076
José Luis PiñanaDepartment of Haematology Hospital Universitari i Politècnic La Fe Valencia Spain.
Ariadna PérezDepartment of Haematology Hospital Clínico Universitario Institute for Research INCLIVA Valencia Spain.
Abdiel QuinteroDepartment of Haematology Hospital Universitari i Politècnic La Fe Valencia Spain.
Juan MontoroDepartment of Haematology Hospital Universitari i Politècnic La Fe Valencia Spain.ORCID https://orcid.org/0000-0003-0024-8068
Juan C Hernández-BoludaDepartment of Haematology Hospital Clínico Universitario Institute for Research INCLIVA Valencia Spain.ORCID https://orcid.org/0000-0002-4289-3113
Carlos CarreteroDepartment of Haematology Hospital Clínico Universitario Institute for Research INCLIVA Valencia Spain.
Aitana Balaguer-RosellóDepartment of Haematology Hospital Universitari i Politècnic La Fe Valencia Spain.
Manuel GuerreiroDepartment of Haematology Hospital Universitari i Politècnic La Fe Valencia Spain.
Ignacio LorenzoDepartment of Haematology Hospital Universitari i Politècnic La Fe Valencia Spain.
Cristóbal AguilarDepartment of Haematology Hospital Universitari i Politècnic La Fe Valencia Spain.
Estela GiménezMicrobiology Service Hospital Clínico Universitario Institute for Research INCLIVA Valencia Spain.
David NavarroMicrobiology Service Hospital Clínico Universitario Institute for Research INCLIVA Valencia Spain.ORCID https://orcid.org/0000-0003-3010-4110
Miguel A SanzDepartment of Haematology Hospital Universitari i Politècnic La Fe Valencia Spain.
Jaime SanzDepartment of Haematology Hospital Universitari i Politècnic La Fe Valencia Spain.
Carlos SolanoDepartment of Haematology Hospital Clínico Universitario Institute for Research INCLIVA Valencia Spain.
Hospital Universitari i Politècnic La Fe · ESUniversitat de València · ESINCLIVA Health Research Institute · ESInstituto de Salud Carlos III · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Sirolimus has emerged as an alternative to calcineurin inhibitors-based (CNI) graft-versus-host disease (GVHD) prophylaxis. This retrospective study compares the outcome of 133 consecutive adult patients with haematological malignancies undergoing haploidentical stem cell transplantation with posttransplant cyclophosphamide (PTCy) and mycophenolate mofetil (MMF), combined with cyclosporine A (PTCy-CsA-MMF,

Indexed as

cyclosporinegraft‐versus‐host disease prophylaxishaploidentical transplantationposttransplant cyclophosphamidesirolimustoxicityviral infections

Identifiers

PMID35845283
PMCPMC9175741
OpenAlexW3137676551

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.