Evidence map›Paper›PMID 35845232›Full record

ArticleObstetric medicine2022

Colorectal cancer during pregnancy or postpartum: Case series and literature review.

Jane E Rogers, Terri L Woodard, Graciela Mn Gonzalez, Arvind Dasari, Benny Johnson, Van K Morris, Bryan Kee, Eduardo Vilar, Y Nancy You, George J Chang and 4 more

Open access · greenAbstract read
In one paragraph

Article in Obstetric medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
0.9field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 17 citations in OpenAlex.

  1. Delphi Initiative for Early-Onset Colorectal Cancer (DIRECt) International Management Guidelines.Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association · 2023
    Guideline
  2. Review
  3. Review
  4. Review
  5. Early-Onset Colorectal Cancer: From Genetic Discovery to Clinical Innovation.American Society of Clinical Oncology educational book. American Society of Clinical Oncology. Annual Meeting · 2025
    Review
  6. Colon Cancer and Pregnancy.Clinics in colon and rectal surgery · 2025
    Review
  7. Review
  8. Article
  9. Gastrointestinal malignancies in pregnancy.Abdominal radiology (New York) · 2023
    Review
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 1 institution in 1 country.

Jane E RogersU.T. M.D. Anderson Cancer Center Pharmacy Clinical Programs, USA.ORCID https://orcid.org/0000-0002-7275-7008
Terri L WoodardDepartment of Gynecologic Oncology and Reproductive Medicine, U.T. M.D. Anderson Cancer Center, USA.
Graciela Mn GonzalezDepartment of Biostatistics, U.T. M.D. Anderson Cancer Center, USA.ORCID https://orcid.org/0000-0002-6350-2206
Arvind DasariDepartment of Gastrointestinal Medical Oncology, U.T. M.D. Anderson Cancer Center, USA.
Benny JohnsonDepartment of Gastrointestinal Medical Oncology, U.T. M.D. Anderson Cancer Center, USA.
Van K MorrisDepartment of Gastrointestinal Medical Oncology, U.T. M.D. Anderson Cancer Center, USA.
Bryan KeeDepartment of Gastrointestinal Medical Oncology, U.T. M.D. Anderson Cancer Center, USA.
Eduardo VilarDepartment of Clinical Cancer Prevention, U.T. M.D. Anderson Cancer Center, USA.
Y Nancy YouDepartment of Surgical Oncology, U.T. M.D. Anderson Cancer Center, USA.
George J ChangDepartment of Surgical Oncology, U.T. M.D. Anderson Cancer Center, USA.
Brian BednarskiDepartment of Surgical Oncology, U.T. M.D. Anderson Cancer Center, USA.
John M SkibberDepartment of Surgical Oncology, U.T. M.D. Anderson Cancer Center, USA.
Miguel A Rodriguez-BigasDepartment of Surgical Oncology, U.T. M.D. Anderson Cancer Center, USA.
Cathy EngDepartment of Gastrointestinal Medical Oncology, U.T. M.D. Anderson Cancer Center, USA.
The University of Texas MD Anderson Cancer Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Colorectal cancer in young adults is on the rise. This rise combined with delayed childbearing increases the likelihood of colorectal cancer diagnosed during pregnancy or in the postpartum period. Methods: Electronic health records were used to identify individuals with colorectal cancer in pregnancy or the postpartum period from 1 August 2007 to 1 August 2019. Results: Forty-two cases were identified. Median age at diagnosis was 33 years. Most (93%) were diagnosed in an advanced stage (III or IV) and had left-sided colorectal cancer tumors (81%). Molecular analysis was completed in 18 (43%) women with microsatellite status available in 40 (95%). The findings were similar to historical controls. Sixty percent were diagnosed in the postpartum period. Common presenting symptoms were rectal bleeding and abdominal pain. Conclusion: Currently there is no consensus recommendation regarding how to manage colorectal cancer during pregnancy. Given the overlapping symptoms with pregnancy, patients often present with advanced disease. We encourage all health care professionals caring for pregnant women to fully evaluate women with persistent gastrointestinal symptoms to rule out colorectal cancer.

Indexed as

cancerColorectal neoplasmgestationalpostpartumpregnancy

Identifiers

PMID35845232
PMCPMC9277731
OpenAlexW3198615853

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.