Evidence map›Paper›PMID 35845135›Full record

ArticleDisease markers2022

Effects of Electroacupuncture on Gastrointestinal Motility Function, Pain, and Inflammation

Xuelai Zhong, Zhaodi Zhang, Jiaying Li, Dandan Liu, Chao Ma, Guonian Wang

Abstract read
In one paragraph

Article in Disease markers, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. [Nan fang yi ke da xue xue bao = Journal of Southern Medical University
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Xuelai ZhongDepartment of Anesthesiology, Harbin Medical University Cancer Hospital, Harbin 150081, China.
Zhaodi ZhangDepartment of Anesthesiology, Harbin Medical University Cancer Hospital, Harbin 150081, China.
Jiaying LiDepartment of Anesthesiology, Harbin Medical University Cancer Hospital, Harbin 150081, China.
Dandan LiuDepartment of Anesthesiology, Harbin Medical University Cancer Hospital, Harbin 150081, China.
Chao MaDepartment of Anesthesiology, The Fourth Hospital of Harbin Medical University, Harbin 150081, China.
Guonian WangDepartment of Anesthesiology, The Fourth Hospital of Harbin Medical University; Pain Research Institute of Heilongjiang Academy of Medical Science, 150 Haping Rd, Nangang District, Harbin 150081, China.ORCID https://orcid.org/0000-0003-1111-9405

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Complications after colon surgery are a major obstacle to postoperative recovery. The purpose of this study was to investigate the effect of electroacupuncture (EA) at Zusanli (ST36) on gastrointestinal motility in rats after colonic anastomosis and the mechanism of transient receptor potential vanillin 1 (TRPV1) channel in regulating gastrointestinal motility, pain, and inflammation. Methods: The rats were randomly divided into six groups, including the control, model, EA, sham-EA, capsaicin, and capsaicin+EA groups, with preoperative capsaicin pretreatment and EA treatment at ST36 acupoint after surgery. Rats were treated using EA at ST36 or sham acupoints after surgery for 5 days. Capsaicin was intraperitoneally injected into rats 3 hours before surgery. Gastrointestinal motility was assessed by measuring the gastric residue, small intestinal propulsion Results: Compared with the model group, electroacupuncture at ST36 point could significantly reduce the residual rate of stomach in rats after operation and increase the propulsive force of the small intestine and the contraction tension of the isolated smooth muscle. Electroacupuncture also increased postoperative day 3 MWT values and decreased postoperative spontaneous nociception scores. In addition, electroacupuncture treatment downregulated the expressions of IL-6, IL-1 Conclusions: Our study showed that electroacupuncture at ST36 acupoint could improve gastrointestinal motility in rats after colonic anastomosis and relieve intestinal inflammation and pain. The mechanism may be to inhibit the activation of NF-

Indexed as

ElectroacupunctureAnimalsCapsaicinGastrointestinal MotilityInflammationNF-kappa BPainRatsTumor Necrosis Factor-alphaCapsaicinNF-kappa BTumor Necrosis Factor-alpha

Identifiers

PMID35845135
PMCPMC9277154

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.