Evidence map›Paper›PMID 35845111›Full record

Article3 Biotech2022

Frustration analysis of TBK1 missense mutations reported in ALS/FTD and cancer patients.

Fatima Khatoon, Vijay Kumar, Farah Anjum, Alaa Shafie, Mohd Adnan, Md Imtaiyaz Hassan

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in 3 Biotech, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 6 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 3 countries.

Fatima KhatoonAmity Institute of Neuropsychology and Neurosciences, Amity University, Noida, Uttar Pradesh 201303 India.
Vijay KumarAmity Institute of Neuropsychology and Neurosciences, Amity University, Noida, Uttar Pradesh 201303 India.
Farah AnjumDepartment of Clinical Laboratory Sciences, College of Applied Medical Sciences, Taif University, Taif, Saudi Arabia.
Alaa ShafieDepartment of Clinical Laboratory Sciences, College of Applied Medical Sciences, Taif University, Taif, Saudi Arabia.
Mohd AdnanDepartment of Biology, College of Science, University of Hail, PO Box 2440, Hail, Saudi Arabia.
Md Imtaiyaz HassanCentre for Interdisciplinary Research in Basic Sciences, Jamia Millia Islamia, New Delhi, 110025 India.ORCID 0000-0002-3663-4940
Amity University · INTaif University · SAJamia Millia Islamia · INUniversity of Ha'il · SA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Tank-binding kinase 1 (TBK1) is a multifunctional kinase having essential roles in cellular processes, autophagy/mitophagy, and selective clearance of damaged proteins. More than 90 mutations in the Supplementary Information: The online version contains supplementary material available at 10.1007/s13205-022-03240-0.

Indexed as

Amyotrophic lateral sclerosisAutophagyCancerComparative genomicsFronto-temporal dementiaLocal frustrationTank-binding kinase 1

Identifiers

PMID35845111
PMCPMC9283588
OpenAlexW4285391134

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.