ArticleExploration (Beijing, China)2022
Super-resolution analyzing spatial organization of lysosomes with an organic fluorescent probe.
Article in Exploration (Beijing, China), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed.
- Super-Resolution Microscopy as a Versatile Tool in Probing Molecular Assembly.International journal of molecular sciences · 2024Review
- Enhanced optical imaging and fluorescent labeling for visualizing drug molecules within living organisms.Acta pharmaceutica Sinica. B · 2024Review
- Article
- Pulmonary inhalation for disease treatment: Basic research and clinical translations.Materials today. Bio · 2024Review
- Probing the dynamic crosstalk of lysosomes and mitochondria with structured illumination microscopy.Trends in analytical chemistry : TRAC · 2023Article
- A general design of pyridinium-based fluorescent probes for enhancing two-photon microscopy.Biosensors & bioelectronics · 2023Article
- Quantifying cell viability through organelle ratiometric probing.Chemical science · 2023Article
- Advanced imaging techniques for tracking drug dynamics at the subcellular level.Advanced drug delivery reviews · 2023Review
- The role of the mitochondrial outer membrane protein SLC25A46 in mitochondrial fission and fusion.Life science alliance · 2023Article
- Constant Conversion Rate of Endolysosomes Revealed by a pH-Sensitive Fluorescent Probe.ACS sensors · 2023Article
- Highly Stable Liposomes Based on Tetraether Lipids as a Promising and Versatile Drug Delivery System.Materials (Basel, Switzerland) · 2022Article
- Super-resolution analyzing spatial organization of lysosomes with an organic fluorescent probe.Exploration (Beijing, China) · 2022Article
- An Endoplasmic Reticulum-Targeted Ratiometric Fluorescent Molecule Reveals ZnFrontiers in pharmacology · 2022Article
- Restoration of Sarco/Endoplasmic Reticulum CaFrontiers in pharmacology · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
Abstract
Lysosomes are multifunctional organelles involved in macromolecule degradation, nutrient sensing and autophagy. Live imaging has revealed lysosome subpopulations with dynamics and characteristic cellular localization. An as-yet unanswered question is whether lysosomes are spatially organized to coordinate and integrate their functions. Combined with super-resolution microscopy, we designed a small organic fluorescent probe, TPAE, that targeted lysosomes with a large Stokes shift. When we analyzed the spatial organization of lysosomes against mitochondria in different cell lines with this probe, we discovered different distance distribution patterns between lysosomes and mitochondria during increased autophagy flux. By using
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.