ArticleFood science & nutrition2022
Effects of dietary protein level on small intestinal morphology, occludin protein, and bacterial diversity in weaned piglets.
Article in Food science & nutrition, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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7 citing papers in PubMed, 8 citations in OpenAlex.
- Effects of Dietary Crude Protein Level on Growth Performance, Immune Function, and Serum Metabolic Profile in Weaned Piglets.Animals : an open access journal from MDPI · 2026Article
- Targeting the Gut Microbiota: Mechanistic Investigation of Polyphenol Modulation of the Gut-Brain Axis in Alzheimer's Disease.International journal of molecular sciences · 2026Review
- Influence of Nutritional Strategies on Performance, Gut Barrier Function and Microbiota Composition in Weaned Piglets.Animals : an open access journal from MDPI · 2025Article
- Productive, Physiological, and Environmental Implications of Reducing Crude Protein Content in Swine Diets: A Review.Animals : an open access journal from MDPI · 2024Review
- Dietary nutrition, intestinal microbiota dysbiosis and post-weaning diarrhea in piglets.Animal nutrition (Zhongguo xu mu shou yi xue hui) · 2024Review
- Nutrition strategies to control post-weaning diarrhea of piglets: From the perspective of feeds.Animal nutrition (Zhongguo xu mu shou yi xue hui) · 2024Review
- Effects of dietary protein level on small intestinal morphology, occludin protein, and bacterial diversity in weaned piglets.Food science & nutrition · 2022Article
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Authors and funding
13 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Due to the physiological characteristics of piglets, the morphological structure and function of the small intestinal mucosa change after weaning, which easily leads to diarrhea in piglets. The aim of this study was to investigate effects of crude protein (CP) levels on small intestinal morphology, occludin protein expression, and intestinal bacteria diversity in weaned piglets. Ninety-six weaned piglets (25 days of age) were randomly divided into four groups and fed diets containing 18%, 20%, 22%, and 24% protein. At 6, 24, 48, 72, and 96 h, changes in mucosal morphological structure, occludin mRNA, and protein expression and in the localization of occludin in jejunal and ileal tissues were evaluated. At 6, 24, and 72 h, changes in bacterial diversity and number of the ileal and colonic contents were analyzed. Results showed that structures of the jejunum and the ileum of piglets in the 20% CP group were intact. The expression of occludin mRNA and protein in the small intestine of piglets in the 20% CP group were significantly higher than those in the other groups. As the CP level increased, the number of pathogens, such as
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