Evidence map›Paper›PMID 35844873›Full record

ArticleFrontiers in public health2022

Comparison of the First and Second Wave of Infections by SARS-CoV-2: A Retrospective and Longitudinal Study From a Primary Health Care Center in Santiago of Chile.

Claudio Acuña-Castillo, Ailen Inostroza-Molina, Sergio A Castro, Sonia Molina-Cabrera, Elías Leiva-Salcedo, Denise Riquelme, Roberto Luraschi, Carlos Barrera-Avalos, Eva Vallejos-Vidal, Andrea Mella-Torres and 9 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in public health, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors at 7 institutions in 3 countries.

Claudio Acuña-CastilloCentro de Biotecnología Acuícola, Facultad de Química y Biología, Universidad de Santiago de Chile, Santiago, Chile.
Ailen Inostroza-MolinaCentro de Salud Familia San José de Chuchunco, Santiago, Chile.
Sergio A CastroLaboratorio de Ecología y Biodiversidad, Facultad de Química y Biología, Universidad de Santiago de Chile, Santiago, Chile.
Sonia Molina-CabreraCentro de Salud Familia San José de Chuchunco, Santiago, Chile.
Elías Leiva-SalcedoDepartamento de Biología, Facultad de Química y Biología, Universidad de Santiago de Chile, Santiago, Chile.
Denise RiquelmeDepartamento de Biología, Facultad de Química y Biología, Universidad de Santiago de Chile, Santiago, Chile.
Roberto LuraschiCentro de Biotecnología Acuícola, Facultad de Química y Biología, Universidad de Santiago de Chile, Santiago, Chile.
Carlos Barrera-AvalosCentro de Biotecnología Acuícola, Facultad de Química y Biología, Universidad de Santiago de Chile, Santiago, Chile.
Eva Vallejos-VidalCentro de Biotecnología Acuícola, Facultad de Química y Biología, Universidad de Santiago de Chile, Santiago, Chile.
Andrea Mella-TorresCentro de Biotecnología Acuícola, Facultad de Química y Biología, Universidad de Santiago de Chile, Santiago, Chile.
Daniel ValdésCentro de Biotecnología Acuícola, Facultad de Química y Biología, Universidad de Santiago de Chile, Santiago, Chile.
Claudio TorresDepartment of Neurobiology Drexel University, Philadelphia, PA, United States.
Kevin MaiseyCentro de Biotecnología Acuícola, Facultad de Química y Biología, Universidad de Santiago de Chile, Santiago, Chile.
Alejandro EscobarLaboratorio Biología Celular y Molecular, Facultad de Odontología, Instituto de Investigación en Ciencias Odontológicas, Universidad de Chile, Santiago, Chile.
Sebastián Reyes-CerpaCentro de Genómica y Bioinformática, Facultad de Ciencias, Universidad Mayor, Santiago, Chile.
Daniela Toro-AscuyLaboratorio de Virología, Facultad de Ciencias de la Salud, Instituto de Ciencias Biomedicas, Universidad Autónoma de Chile, Santiago, Chile.
Mónica ImaraiCentro de Biotecnología Acuícola, Facultad de Química y Biología, Universidad de Santiago de Chile, Santiago, Chile.
Felipe E Reyes-LópezCentro de Biotecnología Acuícola, Facultad de Química y Biología, Universidad de Santiago de Chile, Santiago, Chile.
Ana María SandinoCentro de Biotecnología Acuícola, Facultad de Química y Biología, Universidad de Santiago de Chile, Santiago, Chile.
Universidad de Santiago de Chile · CLDrexel University · USUniversidad Autónoma de Chile · CLUniversidad Mayor · CLUniversitat Autònoma de Barcelona · ESUniversity of Chile · CLUniversity of the Americas · CL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The current COVID-19 pandemic is caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Many countries have reported the experience of at least two contagion waves, describing associated mortality rates and population behavior. The analysis of the effect of this pandemic in different localities can provide valuable information on the key factors to consider in the face of future massive infectious diseases. This work describes the first retrospective and comparative study about behavior during the first and second waves of the COVID-19 pandemic in Chile from a primary Healthcare Center. From 19,313 real-time quantitative PCR (RT-qPCR) tests assessed, the selected 1,694 positive diagnostics showed a decrease in mortality rate in the second wave (0.6%) compared with the first (4.6%). In addition, we observed that infections in the second wave were mainly in young patients with reduced comorbidities. The population with a complete vaccination schedule shows a decrease in the duration of symptoms related to the disease, and patients with more comorbidities tend to develop severe illness. This report provides evidence to partially understand the behavior and critical factors in the severity of the COVID-19 pandemic in the population of Santiago of Chile.

Indexed as

COVID-19SARS-CoV-2ChileHumansLongitudinal StudiesPandemicsPrimary Health CareRetrospective StudiesChileCOVID-19SARS-CoV-2vaccinationwaves of infection

Identifiers

PMID35844873
PMCPMC9280347
OpenAlexW4283754667

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.