Evidence map›Paper›PMID 35844706›Full record

ArticleEJHaem2021

A mutant fibrinogen that is unable to form fibrin can improve renal phenotype in mice with sickle cell anemia.

Marilou G Narciso, Blair Hoeting, Jeanne M James, Katherine VandenHeuvel, Md Nasimuzzaman

Open access · diamondAbstract read
In one paragraph

Article in EJHaem, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Marilou G NarcisoDivision of Experimental Hematology and Cancer Biology Cincinnati Children's Hospital Medical Center Cincinnati Ohio USA.
Blair HoetingDivision of Experimental Hematology and Cancer Biology Cincinnati Children's Hospital Medical Center Cincinnati Ohio USA.
Jeanne M JamesDivision Pediatric Cardiology Medical College of Wisconsin Milwaukee Wisconsin USA.
Katherine VandenHeuvelPathology Core Cincinnati Children's Hospital Medical Center Cincinnati Ohio USA.
Md NasimuzzamanDivision of Experimental Hematology and Cancer Biology Cincinnati Children's Hospital Medical Center Cincinnati Ohio USA.ORCID https://orcid.org/0000-0002-1543-718X
Cincinnati Children's Hospital Medical Center · USMedical College of Wisconsin · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Sickle cell anemia (SCA) causes nephropathy which may progress to kidney failure. To determine if soluble fibrinogen (Fib

Indexed as

albuminuriafibrinogenkidneynephropathypathologysickle cell anemiathrombin

Identifiers

PMID35844706
PMCPMC9176143
OpenAlexW3169521607

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.