Evidence map›Paper›PMID 35844584›Full record

ArticleFrontiers in immunology2022

TIGIT Deficiency Protects Mice From DSS-Induced Colitis by Regulating IL-17A-Producing CD4

Binfeng Chen, Baokui Ye, Mengyuan Li, Shuyi Wang, Jin Li, Yimei Lai, Niansheng Yang, Zunfu Ke, Hui Zhang

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 27 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. TIGIT deficiency promotes autoreactive CD4Nature communications · 2025
    Article
  9. Article
  10. Article
  11. Review
  12. Review
  13. Article
  14. Article
  15. Article
  16. TIGIT regulates CD4Frontiers in immunology · 2024
    Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Binfeng ChenDepartment of Rheumatology, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.
Baokui YeDepartment of Rheumatology, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.
Mengyuan LiDepartment of Rheumatology, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.
Shuyi WangDepartment of Rheumatology, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.
Jin LiDepartment of Rheumatology, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.
Yimei LaiDepartment of Rheumatology, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.
Niansheng YangDepartment of Rheumatology, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.
Zunfu KeDepartment of Pathology, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.
Hui ZhangDepartment of Rheumatology, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.
Sun Yat-sen University · CNThe First Affiliated Hospital, Sun Yat-sen University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Tissue-resident memory T cells (T

Indexed as

ColitisInflammatory Bowel DiseasesAnimalsCD4-Positive T-LymphocytesImmunologic MemoryInflammationInterleukin-17Memory T CellsMiceReceptors, ImmunologicInterleukin-17Receptors, ImmunologicT cell Ig and ITIM domain protein, mouseDSS-induced colitisinflammatory bowel diseasesinterleukin-17ATIGITtissue-resident memory T cells

Identifiers

PMID35844584
PMCPMC9283574
OpenAlexW4283756622

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.