Evidence map›Paper›PMID 35844379›Full record

ArticleSaudi journal of biological sciences2022

Population and mutational assessment of novel repeats in 13RM Y-STRs in unrelated males born in Gilgit, Pakistan.

Muhammad Farhat Ullah, Absar Ali, Aqsa Majeed, Aqsa Ijaz, Abdulla Albastaki, Muhammad Ijaz Khan, Muhammad Ramzan Khan, Huda Ahmed Alghamdi, Mohammed Abdulrahman Alshahrani

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Saudi journal of biological sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Muhammad Farhat UllahGenome Editing & Sequencing Lab, National Centre for Bioinformatics, Quaid-i-Azam University, Islamabad, Pakistan.
Absar AliGenome Editing & Sequencing Lab, National Centre for Bioinformatics, Quaid-i-Azam University, Islamabad, Pakistan.
Aqsa MajeedGenome Editing & Sequencing Lab, National Centre for Bioinformatics, Quaid-i-Azam University, Islamabad, Pakistan.
Aqsa IjazGenome Editing & Sequencing Lab, National Centre for Bioinformatics, Quaid-i-Azam University, Islamabad, Pakistan.
Abdulla AlbastakiGeneral Department of Forensic Sciences and Criminology, Dubai Police G.H.Q., Dubai, United Arab Emirates.
Muhammad Ijaz KhanDepartment of Mathematics and Statistics, Riphah International University I-14, Islamabad 44000, Pakistan.
Muhammad Ramzan KhanGenome Editing & Sequencing Lab, National Centre for Bioinformatics, Quaid-i-Azam University, Islamabad, Pakistan.
Huda Ahmed AlghamdiDepartment of Biology, College of Sciences, King Khalid University, Abha, Saudi Arabia.
Mohammed Abdulrahman AlshahraniDepartment of Clinical Laboratory Sciences, Faculty of Applied Medical Sciences, Najran University, P.O. Box 1988, Najran 61441, Saudi Arabia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Because they are totally transferred to the future generations until mutations occur, Y chromosome genetic markers are commonly utilised in forensics for the classification of male lineages for criminal justice purposes. The mutation rate of Rapidly Mutating Y-STRs (RM Y-STRs) markers is high. That is not seen in other Y-STRs markers, and they appear to be effective in distinguishing paternally related men. This study aimed to estimate the population and mutational parameters of 13 RM Y-STRs in 13 unrelated males born in Gilgit, Pakistan. Repeat there was no population substructure and strong discriminating capacity in the counts. In this population, there were higher mutation rates with the unusual structure of repeats. More research is needed to better characterize these loci in diverse Pakistani groups.

Indexed as

Bio-Edit, Biological sequence alignment editorISFG, International Society of Forensic GeneticsMutation ratesPCR, Polymerase chain reactionRapidly mutatingRM Y-STR, Rapidly mutating Y-Chromosomal Short Tandem RepeatSTRSTRs, Short Tandem RepeatsY chromosomeY-STR, Y-Chromosomal Short Tandem Repeat

Identifiers

PMID35844379
PMCPMC9280172

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.