Evidence map›Paper›PMID 35844245›Full record

ArticleFrontiers in systems neuroscience2022

Unilateral Perforant Path Transection Does Not Alter Lateral Entorhinal Cortical or Hippocampal CA3

Tara L Cooper, John J Thompson, Sean M Turner, Cory Watson, Katelyn N Lubke, Carly N Logan, Andrew P Maurer, Sara N Burke

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in systems neuroscience, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.1field-weighted citation impact, top 59% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Tara L CooperDepartment of Neuroscience, Evelyn F. McKnight Brain Institute, University of Florida, Gainesville, FL, United States.
John J ThompsonDepartment of Neuroscience, Evelyn F. McKnight Brain Institute, University of Florida, Gainesville, FL, United States.
Sean M TurnerDepartment of Neuroscience, Evelyn F. McKnight Brain Institute, University of Florida, Gainesville, FL, United States.
Cory WatsonDepartment of Neuroscience, Evelyn F. McKnight Brain Institute, University of Florida, Gainesville, FL, United States.
Katelyn N LubkeDepartment of Neuroscience, Evelyn F. McKnight Brain Institute, University of Florida, Gainesville, FL, United States.
Carly N LoganDepartment of Neuroscience, Evelyn F. McKnight Brain Institute, University of Florida, Gainesville, FL, United States.
Andrew P MaurerDepartment of Neuroscience, Evelyn F. McKnight Brain Institute, University of Florida, Gainesville, FL, United States.
Sara N BurkeDepartment of Neuroscience, Evelyn F. McKnight Brain Institute, University of Florida, Gainesville, FL, United States.
University of Florida · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

It is well established that degradation of perforant path fibers is associated with age-related cognitive dysfunction and CA3 hyperactivity. Whether this fiber loss triggers a cascade of other functional changes within the hippocampus circuit has not been causatively established, however. Thus, the current study evaluated the effect of perforant path fiber loss on neuronal activity in CA3 and layer II of the lateral entorhinal cortex (LEC) in relation to mnemonic similarity task performance. Expression of the immediate early gene

Indexed as

entorhinal cortexhippocampusimmediate early genemnemonic similarity taskrat

Identifiers

PMID35844245
PMCPMC9279555
OpenAlexW4283763189

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.