Evidence map›Paper›PMID 35844138›Full record

ArticleThe Journal of physiology2022

Sympathetic neural reactivity to the Trier social stress test.

Jeremy A Bigalke, Ian M Greenlund, Jennifer R Nicevski, Anne L Tikkanen, Jason R Carter

Abstract read
In one paragraph

Article in The Journal of physiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Guidelines for rigor and reproducibility of heart rate variability within human cardiovascular research.American journal of physiology. Heart and circulatory physiology · 2026
    Review
  2. Review
  3. Article
  4. Article
  5. Article
  6. Actigraphy-based sleep and muscle sympathetic nerve activity in humans.American journal of physiology. Regulatory, integrative and comparative physiology · 2024
    Article
  7. Article
  8. Blood pressure and muscle sympathetic nerve activity are associated with trait anxiety in humans.American journal of physiology. Heart and circulatory physiology · 2023
    Article
  9. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors.

Jeremy A BigalkeDepartment of Health and Human Development, Montana State University, Bozeman, MT, USA.ORCID 0000-0002-1653-4563
Ian M GreenlundDepartment of Health and Human Development, Montana State University, Bozeman, MT, USA.
Jennifer R NicevskiDepartment of Health and Human Development, Montana State University, Bozeman, MT, USA.
Anne L TikkanenDepartment of Health and Human Development, Montana State University, Bozeman, MT, USA.
Jason R CarterDepartment of Health and Human Development, Montana State University, Bozeman, MT, USA.ORCID 0000-0001-7350-6537

Funding

Research Core (Developmental Research Project Program)P20GM103474 · NIGMS · MONTANA STATE UNIVERSITY - BOZEMAN · PI Ann Therese Bertagnolli · 2012 to 2026
$60.0M
Tracking and Evaluation CoreU54GM115371 · NIGMS · MONTANA STATE UNIVERSITY - BOZEMAN · PI HOPKINS, SCARLETT H · 2016 to 2020
$20.9M
Alcohol and Neurovascular Control in HumansR01AA024892 · NIAAA · MONTANA STATE UNIVERSITY - BOZEMAN · PI CARTER, JASON R · 2017 to 2021
$1.8M
NIAAA NIH HHS R01 AA024892NIGMS NIH HHS P20 GM103474NIGMS NIH HHS U54 GM115371
6 · The paper itself

Abstract

Sympathetic responsiveness to laboratory mental stress is highly variable, making interpretations of its role in stress reactivity challenging. The present study assessed muscle sympathetic nerve activity (MSNA, microneurography) responsiveness to the Trier social stress test (TSST), which employs an anticipatory stress phase, followed by a public speaking and mental arithmetic task. We hypothesized that sympathetic reactivity to the anticipatory phase would offer a more uniform response between individuals due to elimination of confounds (i.e. respiratory changes, muscle movement, etc.) observed during more common stress tasks. Participants included 26 healthy adults (11 men, 15 women, age: 25 ± 6 years, body mass index: 24 ± 3 kg/m

Indexed as

Psychological TestsSympathetic Nervous SystemAdultBlood PressureFemaleHeart RateHumansMaleMuscle, SkeletalStress, PsychologicalYoung Adultmental stressmuscle sympathetic nerve activityTrier social stress test

Identifiers

PMID35844138
PMCPMC9401978

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.