Evidence map›Paper›PMID 35843950›Full record

ArticleBMC oral health2022

Changes in oral function, swallowing function, and quality of life in patients with head and neck cancer: a prospective cohort study.

Yoshiaki Ihara, Hirotaka Kato, Yuichi Tashimo, Yoshiki Iizumi, Yuma Fukunishi, Hitoshi Sato, Toshikazu Shimane, Koji Takahashi

Open access · goldAbstract read
In one paragraph

Article in BMC oral health, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
4.5field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it, 18 citations in OpenAlex.

  1. Pooled it
  2. The impact of a simple positioning aid device on the diagnostic performance of thyroid cancer in CT scans: a randomized controlled trial.Cancer imaging : the official publication of the International Cancer Imaging Society · 2025
    Trial
  3. Article
  4. Post-radiotherapy xerostomia and quality of life in head and neck cancer patients.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
    Article
  5. Article
  6. Article
  7. Review
  8. Review
  9. Observational
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
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  16. Article
  17. Lip Seal Strength and Tongue Pressure among Japanese Male Workers: Comparison of Different Age Groups.International journal of environmental research and public health · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Yoshiaki IharaDivision of Oral Functional Rehabilitation Medicine, Department of Special Needs Dentistry, School of Dentistry, Showa University, Kitasenzoku 2-1-1, Oh-taku, Tokyo, 145-8515, Japan. ikkun@dent.showa-u.ac.jp.ORCID 0000-0002-4324-2670
Hirotaka KatoDivision of Oral Functional Rehabilitation Medicine, Department of Special Needs Dentistry, School of Dentistry, Showa University, Kitasenzoku 2-1-1, Oh-taku, Tokyo, 145-8515, Japan.
Yuichi TashimoDivision of Oral Functional Rehabilitation Medicine, Department of Special Needs Dentistry, School of Dentistry, Showa University, Kitasenzoku 2-1-1, Oh-taku, Tokyo, 145-8515, Japan.
Yoshiki IizumiDivision of Oral Functional Rehabilitation Medicine, Department of Special Needs Dentistry, School of Dentistry, Showa University, Kitasenzoku 2-1-1, Oh-taku, Tokyo, 145-8515, Japan.
Yuma FukunishiDivision of Oral Functional Rehabilitation Medicine, Department of Special Needs Dentistry, School of Dentistry, Showa University, Kitasenzoku 2-1-1, Oh-taku, Tokyo, 145-8515, Japan.
Hitoshi SatoHead and Neck Oncology Center, Showa University Hospital, Tokyo, Japan.
Toshikazu ShimaneHead and Neck Oncology Center, Showa University Hospital, Tokyo, Japan.
Koji TakahashiDivision of Oral Functional Rehabilitation Medicine, Department of Special Needs Dentistry, School of Dentistry, Showa University, Kitasenzoku 2-1-1, Oh-taku, Tokyo, 145-8515, Japan.
Showa University · JPShowa University Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundHead and neck cancer (HNC) treatment can cause oral morbidities, such as oral dryness and dysphagia, affecting the patient's quality of life (QOL). The relationship between oral functions and QOL in patients with early-stage HNC remains poorly studied. This study aimed to evaluate changes in the QOL of patients with early-stage HNC and identify factors that affect the QOL of these patients.

methodsIn this prospective cohort study, 37 patients who underwent early-stage (Stage I/Stage II) HNC treatment were evaluated for their oral function, swallowing function, and the QOL score at baseline (BL) and 12 months after surgical treatment (12 M). The participants were divided into two groups: patients who returned to the BL QOL score at 12 M (RE; n = 26) and those who did not (NR; n = 11).

resultsIn total, 29.7% (11/37) patients with early-stage HNC did not return to the BL QOL score at 12 M. There was no significant difference between the RE and NR groups regarding the oral and swallowing function. Moreover, oral and swallowing function of all patients returned to the BL at 12 M. The NR group showed lower QOL scores than the RE group in the global health status, and "sticky saliva" parameters in the questionnaires.

conclusionRestoration of the oral function is insufficient to improve the QOL of patients with early-stage HNC. The treatment of these patients should instead consider several factors that affect their QOL.

Indexed as

Deglutition DisordersHead and Neck NeoplasmsDeglutitionHumansProspective StudiesQuality of LifeSurveys and QuestionnairesDysphagiaHead and neck cancerMorbidityOral functionQuality of lifeSwallowing

Identifiers

PMID35843950
PMCPMC9288711
OpenAlexW4285676877

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.