ReviewInternational dental journal2022
A Review of the Protocol of SDF Therapy for Arresting Caries.
Review in International dental journal, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07658690 (The Effectiveness of Single and Dual Silver Fluoride), which is not on this map. Cited by 23 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
The Effectiveness of Single and Dual Silver Fluoride (SF) Applications on Dentine Caries Among Malaysian Preschool Children: A Randomised Controlled Trial
Who cites it
23 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Color change of tooth-colored restorative materials bonded to silver diamine fluoride-treated dentine: a systematic review.BMC oral health · 2024Pooled it
- Effects of light curing on silver diamine fluoride-treated carious lesions: A systematic review.PloS one · 2024Pooled it
- A Randomized Controlled Trial of Silver Diamine Fluoride Application Time.Journal of dental research · 2025Trial
- Knowledge, attitude and practice of paediatric dentists towards silver diammine fluoride in Egypt: a national survey.European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry · 2026Article
- Knowledge and attitudes regarding silver diamine fluoride among Brazilian dentists: a cross-sectional study.European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry · 2026Article
- Quality of YouTube™ videos on the clinical use of silver fluoride.European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry · 2025Article
- Two-Year Bonding Performances of a Universal Adhesive After Dentin Pre-Treatment With Two-Step Silver-Containing Solutions.The journal of adhesive dentistry · 2025Article
- Effect of Silver Diamine Fluoride Application Methods on Dentin Microhardness and Durability Under pH Cycling: An In Vitro Study.Clinical and experimental dental research · 2025Article
- Impact of silver diamine fluoride on composite resin bond strength: An In vitro study with various adhesive systems.Heliyon · 2025Article
- Cariostatic Agents: From Silver Diamine Fluoride to Emerging Bioactive Compounds.Clinical, cosmetic and investigational dentistry · 2025Review
- Survival of Silver Diamine Fluoride Varnish Treated Teeth among Children with Single/Multiple Applications: A Split-mouth Randomized Clinical Trial.International journal of clinical pediatric dentistry · 2024Article
- Clinical, Microbiological, and Microcomputed Tomography Evaluation of Silver Diamine Fluoride in Controlling Root Carious Lesions: AnJournal of clinical and experimental dentistry · 2024Article
- Effect of silver diamine fluoride on nicotine-inducedJADA foundational science · 2024Article
- An updated look at the use of silver diamine fluoride in U.S. dental schools' predoctoral curriculum-a survey.Frontiers in dental medicine · 2024Article
- The use of silver diamine fluoride to prevent/treat enamel carious lesions: a narrative review.PeerJ · 2024Review
- Article
- Stability of Silver and Fluoride Contents in Silver Diamine Fluoride Solutions.International dental journal · 2023Article
- The pharmacokinetics of 38% silver diamine fluoride in healthy children with dental caries: a quasi-experimental study.European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry · 2023Article
- Application of 20% silver nanoclusters in polymethacrylic acid on simulated dentin caries; its penetration depth and effect on surface hardness.Scientific reports · 2023Article
- Teaching of silver diamine fluoride for the management of dental caries and hypersensitivity - situation in the Southeast Asia dental schools.BMC oral health · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveThe aim of this work was to review the protocol of the use of silver diamine fluoride (SDF) for arresting caries, specifically the application time.
methodTwo researchers searched manufacturers' instructions, YouTube videos, and 5 databases (Embase, Medline, PubMed, Scopus, and Web of Science). Manufacturers' instructions, videos from national dental organisations, and peer-reviewed journal articles that published the SDF application protocol in English for arresting caries were selected.
resultsThe review included 14 protocols from 15 publications from 4 manufacturers, 3 dental associations, and 7 author teams (one team had 2 articles). The American Dental Association and the British Society of Paediatric Dentistry provided their SDF application protocols on YouTube. The American Academy of Paediatric Dentistry and 7 author teams published their protocols in journal articles. Seven publications suggested an SDF application time of 60 seconds. Seven publications suggested a time range of 10 seconds to 240 seconds. Two publications suggested caries excavation, but 4 publications suggested no caries excavation before SDF application. The procedures from at least 5 publications involved protecting the gingiva with petroleum jelly, isolating the carious tooth with cotton rolls, drying the carious lesion with a 3-in-1 syringe, applying SDF solution with a micro brush for 60 seconds, removing excess SDF solution with gauze, and applying fluoride varnish to the SDF-treated lesion.
conclusionsAlthough the SDF application protocol is simple and straightforward, the published protocols could be different. Most publications suggested an SDF application time of 60 seconds, which can be long, particularly for young children and older adults.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.