Evidence map›Paper›PMID 35843722›Full record

ArticleZoological research2022

Whole-genome resequencing reveals molecular imprints of anthropogenic and natural selection in wild and domesticated sheep.

De-Yin Zhang, Xiao-Xue Zhang, Fa-Di Li, Lv-Feng Yuan, Xiao-Long Li, Yu-Kun Zhang, Yuan Zhao, Li-Ming Zhao, Jiang-Hui Wang, Dan Xu and 6 more

Open access · diamondAbstract read
In one paragraph

Article in Zoological research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
4.9field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 29 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. A Functional Regulatory Variant ofAnimals : an open access journal from MDPI · 2025
    Article
  8. Article
  9. Review
  10. Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 4 institutions in 2 countries.

De-Yin ZhangState Key Laboratory of Grassland Agro-Ecosystems, Key Laboratory of Grassland Livestock Industry Innovation, Ministry of Agriculture and Rural Affairs, Engineering Research Center of Grassland Industry, Ministry of Education.
Xiao-Xue ZhangCollege of Animal Science and Technology, Gansu Agricultural University, Lanzhou, Gansu 730070, China.
Fa-Di LiState Key Laboratory of Grassland Agro-Ecosystems, Key Laboratory of Grassland Livestock Industry Innovation, Ministry of Agriculture and Rural Affairs, Engineering Research Center of Grassland Industry, Ministry of Education.
Lv-Feng YuanLanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou, Gansu 730046, China.
Xiao-Long LiCollege of Animal Science and Technology, Gansu Agricultural University, Lanzhou, Gansu 730070, China.
Yu-Kun ZhangCollege of Animal Science and Technology, Gansu Agricultural University, Lanzhou, Gansu 730070, China.
Yuan ZhaoCollege of Animal Science and Technology, Gansu Agricultural University, Lanzhou, Gansu 730070, China.
Li-Ming ZhaoCollege of Animal Science and Technology, Gansu Agricultural University, Lanzhou, Gansu 730070, China.
Jiang-Hui WangCollege of Animal Science and Technology, Gansu Agricultural University, Lanzhou, Gansu 730070, China.
Dan XuCollege of Animal Science and Technology, Gansu Agricultural University, Lanzhou, Gansu 730070, China.
Jiang-Bo ChengCollege of Animal Science and Technology, Gansu Agricultural University, Lanzhou, Gansu 730070, China.
Xiao-Bin YangCollege of Animal Science and Technology, Gansu Agricultural University, Lanzhou, Gansu 730070, China.
Wen-Xin LiCollege of Animal Science and Technology, Gansu Agricultural University, Lanzhou, Gansu 730070, China.
Chang-Chun LinCollege of Animal Science and Technology, Gansu Agricultural University, Lanzhou, Gansu 730070, China.
Bu-Bo ZhouCollege of Animal Science and Technology, Gansu Agricultural University, Lanzhou, Gansu 730070, China.
Wei-Min WangState Key Laboratory of Grassland Agro-Ecosystems, Key Laboratory of Grassland Livestock Industry Innovation, Ministry of Agriculture and Rural Affairs, Engineering Research Center of Grassland Industry, Ministry of Education.
Gansu Agricultural University · CNLanzhou University of Technology · CNLanzhou Veterinary Research Institute · CNMinistry of Agriculture · EE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The abundance of domesticated sheep varieties and phenotypes is largely the result of long-term natural and artificial selection. However, there is limited information regarding the genetic mechanisms underlying phenotypic variation induced by the domestication and improvement of sheep. In this study, to explore genomic diversity and selective regions at the genome level, we sequenced the genomes of 100 sheep across 10 breeds and combined these results with publicly available genomic data from 225 individuals, including improved breeds, Chinese indigenous breeds, African indigenous breeds, and their Asian mouflon ancestor. Based on population structure, the domesticated sheep formed a monophyletic group, while the Chinese indigenous sheep showed a clear geographical distribution trend. Comparative genomic analysis of domestication identified several selective signatures, including

Indexed as

GenomeSelection, GeneticAnimalsGenomicsSequence Analysis, DNASheepSheep, DomesticIFI44 geneImmunitySelection signature analysisSheepWhole-genome resequencing

Identifiers

PMID35843722
PMCPMC9486524
OpenAlexW4285126091

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.