Evidence map›Paper›PMID 35843345›Full record

ReviewNeuroscience and biobehavioral reviews2022

Sleep to Internalizing Pathway in Young Adolescents (SIPYA): A proposed neurodevelopmental model.

Saima A Akbar, Aaron T Mattfeld, Angela R Laird, Dana L McMakin

Open access · greenAbstract readReview
In one paragraph

Review in Neuroscience and biobehavioral reviews, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
6.5field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 37 citations in OpenAlex.

  1. Adolescents' daily affect predicts their mobile phone use (not the other way around).Journal of research on adolescence : the official journal of the Society for Research on Adolescence · 2026
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  5. Prospective Pathways Among Rumination, Depression, and Insomnia in Youth.Research on child and adolescent psychopathology · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Saima A AkbarDepartment of Psychology, Florida International University, Miami, FL, USA. Electronic address: saima.akbar@fiu.edu.
Aaron T MattfeldDepartment of Psychology, Florida International University, Miami, FL, USA.
Angela R LairdDepartment of Physics, Florida International University, Miami, FL, USA.
Dana L McMakinDepartment of Psychology, Florida International University, Miami, FL, USA.
Florida International University · US

Funding

Sleep-dependent negative overgeneralization in peri-pubertal anxietyR01MH116005 · NIMH · FLORIDA INTERNATIONAL UNIVERSITY · PI DANA L MCMAKIN, Aaron Mattfeld · 2018 to 2026
$6.9M
NIMH NIH HHS R01 MH116005
6 · The paper itself

Abstract

The prevalence of internalizing disorders, i.e., anxiety and depressive disorders, spikes in adolescence and has been increasing amongst adolescents despite the existence of evidence-based treatments, highlighting the need for advancing theories on how internalizing disorders emerge. The current review presents a theoretical model, called the Sleep to Internalizing Pathway in Young Adolescents (SIPYA) Model, to explain how risk factors, namely sleep-related problems (SRPs), are prospectively associated with internalizing disorders in adolescence. Specifically, SRPs during late childhood and early adolescence, around the initiation of pubertal development, contribute to the interruption of intrinsic brain networks dynamics, both within the default mode network and between the default mode network and other networks in the brain. This interruption leaves adolescents vulnerable to repetitive negative thought, such as worry or rumination, which then increases vulnerability to internalizing symptoms and disorders later in adolescence. Sleep-related behaviors are observable, modifiable, low-stigma, and beneficial beyond treating internalizing psychopathology, highlighting the intervention potential associated with understanding the neurodevelopmental impact of SRPs around the transition to adolescence. This review details support for the SIPYA Model, as well as gaps in the literature and future directions.

Indexed as

AnxietyDepressionAdolescentAnxiety DisordersBrainChildHumansSleepAdolescenceAnxietyDefault mode networkDepressionInternalizingPubertyRepetitive negative thoughtSleepTriple Network model

Identifiers

PMID35843345
PMCPMC10750488
OpenAlexW4285400633

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.