A novel approach for assessment of antitrypanosomal activity of sesquiterpene lactones through additive and non-additive molecular structure parameters.

Mohammad Hossein Keshavarz, Zeinab Shirazi, Faezeh Sayehvand

Abstract read

In one paragraph

Article in Molecular diversity, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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1citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

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3 · Its place in the literature

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1 citing paper in PubMed.

Simultaneous Determination of Fexinidazole and Its Major Metabolites in Rat Plasma by UPLC-MS/MS: Method Validation and Application to Pharmacokinetic Study.Drug design, development and therapy · 2026
Article

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5 · Who and what money

Authors and funding

3 authors.

Mohammad Hossein KeshavarzFaculty of Applied Sciences, Malek Ashtar University of Technology, Shahin-shahr, Iran. mhkeshavarz@mut-es.ac.ir.ORCID http://orcid.org/0000-0001-9269-7527

Zeinab ShiraziFaculty of Applied Sciences, Malek Ashtar University of Technology, Shahin-shahr, Iran.

Faezeh SayehvandFaculty of Applied Sciences, Malek Ashtar University of Technology, Shahin-shahr, Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Human African trypanosomiasis (HAT) or sleeping sickness is a protozoan neglected tropical disease, which is the main health worry in more than 20 countries in Africa. A novel approach is presented to predict the antitrypanosomal activity of sesquiterpene lactones (STLs) in terms of biological activity (pIC

Indexed as

SesquiterpenesTrypanosomiasis, AfricanAnimalsHumansLactonesMolecular StructureReproducibility of ResultsTrypanosoma brucei rhodesienseLactonesSesquiterpenesActivity of antitrypanosomal activityAdditive and non-additive descriptorHuman African trypanosomiasisInternal and external validationMolecular structure

Identifiers

PMID35842884

DOI10.1007/s11030-022-10495-5

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.