ArticleThe journal of nutrition, health & aging2022
Association between Ultra-Processed Food Consumption and Frailty in American Elder People: Evidence from a Cross-Sectional Study.
Article in The journal of nutrition, health & aging, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 3 of them syntheses that pooled it.
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The trial behind it
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Who cites it
20 citing papers in PubMed, 3 syntheses or guidelines pooled it, 47 citations in OpenAlex.
- Ultra-Processed Food Intakes and Health Outcomes in Adults Older Than 60 Years: A Systematic Review.Nutrition reviews · 2025Pooled it
- The association of ultra-processed food intake on age-related muscle conditions: a systematic review and dose-response meta-analysis with meta-regression.Journal of health, population, and nutrition · 2025Pooled it
- Mediterranean Diet and Sarcopenia Features in Apparently Healthy Adults over 65 Years: A Systematic Review.Nutrients · 2023Pooled it
- Association Between Ultra-Processed Food Consumption and Frailty in Korean Older Adults.Nutrients · 2026Article
- Association between ultra-processed foods intake and frailty risk in community-dwelling older adults.Journal of health, population, and nutrition · 2025Article
- Association Between Ultra-Processed Food Consumption Frequency and Frailty: Findings from the InCHIANTI Study of Aging.Geriatrics (Basel, Switzerland) · 2025Article
- Ultra-Processed Food and Frailty: Evidence from a Prospective Cohort Study and Implications for Future Research.Nutrients · 2025Article
- Consumptıon of ultra-processed foods can accelerate age-related appearance of sarcopenıa.Biogerontology · 2025Review
- Comparison of nutrients and ultra-processed food consumption between different phenotypes defined by abdominal obesity and sarcopenia.Frontiers in nutrition · 2025Article
- Mediterranean Diet and Ultra-Processed Food Intake in Older Australian Adults-Associations with Frailty and Cardiometabolic Conditions.Nutrients · 2024Article
- Article
- Ultra-processed foods consumption among a USA representative sample of middle-older adults: a cross-sectional analysis.The British journal of nutrition · 2024Article
- Dietary Patterns and Healthy or Unhealthy Aging.Gerontology · 2024Review
- Cross-sectional and longitudinal associations between empirically derived dietary patterns and frailty among older men: The Concord Health and Ageing in Men Project.The journal of nutrition, health & aging · 2024Article
- The relationship between dietary inflammatory index and osteoporosis among chronic kidney disease population.Scientific reports · 2023Article
- Synthesis of Effect Sizes on Dose Response from Ultra-Processed Food Consumption against Various Noncommunicable Diseases.Foods (Basel, Switzerland) · 2023Review
- Dietary acid load decreases with age and is associated with sagittal abdominal diameter: a nationally representative quantification study in US adults.Aging clinical and experimental research · 2023Article
- Ultra-processed food consumption and nutritional frailty in older age.GeroScience · 2023Article
- Review
- Sodium intake trend and current intake level by meal provision place among the citizens of Seoul.Nutrition research and practice · 2023Article
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesOur study aims to explore the association between ultra-processed foods (UPFs) and frailty in participants with different body mass indexes (BMIs).
designA cross-sectional study.
settingData were collected from the National Health and Nutrition Examination Survey (NHANES) 1999-2000 and 2001-2002.
participantsWe analyzed data from 2,329 participants. MEASUREMENTS: Dietary data were obtained using 24-h dietary recall method. Frail status was assessed by modified Fried frailty phenotype. The association between the grams, energy, and energy proportion of UPFs and the risk of pre-frailty/frailty was estimated using logistic regression analysis, and odds ratio (OR) with 95% confidence intervals (CIs) were calculated. Participants were categorized into underweight-normal weight (BMI <25 kg/m2), overweight (25 kg/m2 ≤ BMI < 30 kg/m2), and obesity (BMI ≥ 30 kg/m2) groups. The multiplicative interaction between BMIs and UPFs on pre-frailty/frailty was assessed using the logistic regression analysis.
resultsWe analyzed data from 2,329 participants, and 2,267 (97.77%) of whom consumed UPFs. There were 1,063 participants in pre-frailty or frailty group and 1,266 participants in non-frailty group. In underweight-normal weight participants, every 100 kcal increase in energy of UPFs intake was associated with increased 0.08 times of pre-frailty or frailty risk (OR: 1.08, 95%CI: 1.00-1.16, P = 0.045), and every 10% increase in energy proportion of UPFs intake was correlated with a 0.02-fold increase in pre-frailty or frailty risk (OR: 1.02, 95%CI: 1.00-1.03, P = 0.018). Similar results were found in overweight participants, with OR of 1.06 (95%CI: 1.01-1.10) and 1.01 (95%CI: 1.00-1.02) for energy and energy proportion, respectively (both P < 0.05). This association was not found in obesity participants.
conclusionThe energy and energy proportion of UPFs intake was positively associated with the frailty risk in underweight-normal weight and overweight people, indicating that population with BMI less than 30 kg/m2 should pay more attention to reasonable diet and balanced source of energy intake.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.