Evidence map›Paper›PMID 35842734›Full record

ArticleImplementation science communications2022

Providing "a beam of light to see the gaps": determinants of implementation of the Systems Analysis and Improvement Approach applied to the pediatric and adolescent HIV cascade in Kenya.

Kristin Beima-Sofie, Anjuli D Wagner, Caroline Soi, Wenjia Liu, Deanna Tollefson, Irene N Njuguna, Emily Ogutu, Douglas Gaitho, Nancy Mburu, Geoffrey Oluoch and 7 more

Abstract read
In one paragraph

Article in Implementation science communications, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Kristin Beima-Sofie *Department of Global Health, University of Washington, Seattle, USA.
Anjuli D Wagner *Department of Global Health, University of Washington, Seattle, USA. anjuliw@uw.edu.ORCID http://orcid.org/0000-0002-5851-1220
Caroline SoiDepartment of Global Health, University of Washington, Seattle, USA.
Wenjia LiuDepartment of Child, Family & Population Health Nursing, University of Washington, Seattle, USA.
Deanna TollefsonDepartment of Global Health, University of Washington, Seattle, USA.
Irene N NjugunaDepartment of Global Health, University of Washington, Seattle, USA.
Emily OgutuGangarosa Department of Environmental Health, Emory University, Atlanta, USA.
Douglas GaithoNetwork of AIDS Researchers in Eastern and Southern Africa, Nairobi, Kenya.
Nancy MburuNetwork of AIDS Researchers in Eastern and Southern Africa, Nairobi, Kenya.
Geoffrey OluochNetwork of AIDS Researchers in Eastern and Southern Africa, Nairobi, Kenya.
Peter MwauraNetwork of AIDS Researchers in Eastern and Southern Africa, Nairobi, Kenya.
Peter CherutichMinistry of Health, Nairobi, Kenya.
Laura OyiengoMinistry of Health, Nairobi, Kenya.
Grace C John-StewartDepartment of Global Health, University of Washington, Seattle, USA.
Ruth NduatiNetwork of AIDS Researchers in Eastern and Southern Africa, Nairobi, Kenya.
Kenneth SherrDepartment of Global Health, University of Washington, Seattle, USA.
Sarah GimbelDepartment of Global Health, University of Washington, Seattle, USA.

Funding

University of Washington/Fred Hutch Center for AIDS ResearchP30AI027757 · NIAID · UNIVERSITY OF WASHINGTON · PI Judith Tsui · 1988 to 2026
$104.9M
NPGH LEADERs YR12: OBSSR (Greenberg, Ngwafong Mukere) & NIBIB (Lee)D43TW009345 · FIC · UNIVERSITY OF WASHINGTON · PI Dibyadyuti Datta, Chandy C. John · 2017 to 2026
$15.2M
Northern/Pacific Universities Global Health Research Training ConsortiumR25TW009345 · FIC · UNIVERSITY OF WASHINGTON · PI KOLARS, JOSEPH C., NERURKAR, VIVEK RAMCHANDRA · 2012 to 2016
$5.9M
Systems analysis and improvement approach to optimize the pediatric HIV diagnosis and care cascade (SAIA-PEDS)R34AI129900 · NIAID · UNIVERSITY OF WASHINGTON · PI SHERR, KENNETH · 2017 to 2019
$622k
Systems analysis and improvement approach to improve pediatric HIV testing and linkage to careF32HD088204 · NICHD · UNIVERSITY OF WASHINGTON · PI WAGNER, ANJULI DAWN · 2016 to 2019
$168k
FIC NIH HHS D43 TW009345NIAID NIH HHS P30 AI027757NICHD NIH HHS F32 HD088204NIH HHS F32HD088204NIH HHS P30 AI027757NIH HHS R25 TW009345NIH HHS R34AI129900
6 · The paper itself

Abstract

backgroundChildren and adolescents living with HIV have poorer rates of HIV testing, treatment, and virologic suppression than adults. Strategies that use a systems approach to optimize these multiple, linked steps simultaneously are critical to close these gaps.

methodsThe Systems Analysis and Improvement Approach (SAIA) was adapted and piloted for the pediatric and adolescent HIV care and treatment cascade (SAIA-PEDS) at 6 facilities in Kenya. SAIA-PEDS includes three tools: continuous quality improvement (CQI), flow mapping, and pediatric cascade analysis (PedCAT). A predominately qualitative evaluation utilizing focus group discussions (N = 6) and in-depth interviews (N = 19) was conducted with healthcare workers after implementation to identify determinants of implementation. Data collection and analysis were grounded in the Consolidated Framework for Implementation Research (CFIR).

resultsOverall, the adapted SAIA-PEDS strategy was acceptable, and the three tools complemented one another and provided a relative advantage over existing processes. The flow mapping and CQI tools were compatible with existing workflows and resonated with team priorities and goals while providing a structure for group problem solving that transcended a single department's focus. The PedCAT was overly complex, making it difficult to use. Leadership and hierarchy were complex determinants. All teams reported supportive leadership, with some describing in detail how their leadership was engaged and enthusiastic about the SAIA-PEDS process, by providing recognition, time, and resources. Hierarchy was similarly complex: in some facilities, leadership stifled rapid innovation by insisting on approving each change, while at other facilities, leadership had strong and supportive oversight of processes, checking on the progress frequently and empowering teams to test innovative ideas.

conclusionCQI and flow mapping were core components of SAIA-PEDS, with high acceptability and consistent use, but the PedCAT was too complex. Leadership and hierarchy had a nuanced role in implementation. Future SAIA-PEDS testing should address PedCAT complexity and further explore the modifiability of leadership engagement to maximize implementation.

Indexed as

AdolescentCascade analysisConsolidated framework for implementation research (CFIR)Continuous quality improvementFlow mappingHealth systemsHIVImplementation determinantsImplementation sciencePediatricSystems Analysis Improvement Approach (SAIA)Systems engineering

Identifiers

PMID35842734
PMCPMC9287987

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.