ArticleJournal of orthopaedic surgery and research2022
Low cervical vertebral CT value increased early subsidence of titanium mesh cage after anterior cervical corpectomy and fusion.
Article in Journal of orthopaedic surgery and research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
29 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Risk factors for cage subsidence in patients undergoing cervical fusion: a systematic review and meta-analysis.Neurosurgical review · 2026Pooled it
- Evaluating the prognostic role of computed tomography Hounsfield units in anticipating spinal outcomes post-instrumentation: a systematic review and meta-analysis.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2025Pooled it
- Is preoperative cervical range of motion associated with cage subsidence after anterior cervical discectomy and fusion?European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026Article
- A Novel Titanium End-Disc-Assisted Allograft Preparation System for Anterior Cervical Corpectomy and Fusion: Development and Preliminary Biomechanical Evaluation.Bioengineering (Basel, Switzerland) · 2026Article
- C-VBQ and CT hounsfield units for DXA-defined low bone mass screening and their associations with bone turnover markers.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026Article
- AI-planned and robotic-assisted pedicle screw placement improves accuracy and reduces loosening in lumbar fusion for patients with low bone mass: a multicenter study.European journal of orthopaedic surgery & traumatology : orthopedie traumatologie · 2026Article
- Lower deep-to-superficial extensor muscle ratio (DSR) as an independent risk factor for early titanium implant subsidence following single-level anterior cervical corpectomy and fusion.Neurosurgical review · 2026Article
- Predictive efficacy of phantom-less calibration of computed tomography for cage subsidence after anterior cervical discectomy and fusion.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026Article
- MRI-based endplate bone quality scoring system in cervical OPLL: a novel measuring method predicting titanium mesh cage subsidence following ACCF.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026Article
- Preoperative imaging predictors of subsidence of 3D-printed artificial cervical vertebral bodies: a cohort study of 102 patients with nomogram development and validation.BMC musculoskeletal disorders · 2026Article
- Radiomics-based machine learning model integrating preoperative vertebral computed tomography and clinical features to predict cage subsidence after single-level anterior cervical discectomy and fusion with a zero-profile anchored spacer.Journal of orthopaedic surgery and research · 2025Article
- Neurological and Biomechanical Evaluation of 72 Patients with Degenerative Cervical Spondylotic Myelopathy at 3, 6, and 12 Months Following Anterior Cervical Corpectomy and Fusion.Medical science monitor : international medical journal of experimental and clinical research · 2025Article
- An innovative self-stabilised 3D-printed artificial vertebral body designed for clinical application and comparison with the conventional implants.Journal of orthopaedic translation · 2025Article
- Predictive value of vertebral specificity of bone mineral density for cage subsidence among patients undergoing anterior cervical diskectomy and fusion: a retrospective study.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2025Article
- Forearm bone mineral density predicts subsidence of titanium mesh cage after anterior cervical corpectomy and fusion in patients with cervical spondylosis.Journal of orthopaedic surgery and research · 2025Article
- Hounsfield Unit Utilization in Cervical Spine for Bone Quality Assessment: A Scoping Review.Journal of clinical medicine · 2025Review
- Synergistic predictive value of MRI-based vertebral bone quality and CT hounsfield units for postoperative sagittal balance deterioration after cervical laminoplasty.Frontiers in surgery · 2025Article
- Evaluation of the effect of cervical spine bone distribution on fixation in ankylosing spondylitis.Frontiers in bioengineering and biotechnology · 2025Article
- Overloaded Vertebral Body Following Consecutive Three-Level Hybrid Surgery Comparing with Anterior Cervical Discectomy and Fusion.Orthopaedic surgery · 2024Article
- The influence of proliferative tissue on Hounsfield unit and its correlation with BMD in middle-aged and elderly patients with lumbar degenerative diseases.Journal of orthopaedic surgery and research · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
STUDY
designThis study was a retrospective review.
objectiveTo study the predictive effect of Hounsfield units (HU) value in the cervical vertebral body derived from computed tomography (CT) on the early titanium mesh cage (TMC) subsidence after anterior cervical corpectomy and fusion (ACCF).
methodsThis retrospective study was conducted on patients who underwent ACCF at one institution between January 2014 and December 2018. We collected date included age, gender, body mass index (BMI), disease type, surgical segment, whether merge ACDF, HU value of the vertebral body and endplate, vertebral body height loss, cervical lordosis angle, and cervical sagittal alignment. VAS, JOA, and NDI were used to assess clinical efficacy. Univariate analysis was performed to screen the influencing factors of TMC subsidence, and then logistic regression was used to find out the independent risk factors. The ROC curve and area under curve (AUC) were used to analyze the HU value to predict the TMC subsidence.
resultsA total of 85 patients who accepted ACCF were included in this study, and early titanium mesh cage subsidence was demonstrated in 29 patients. The subsidence rate was 34.1%. The JOA, VAS, and NDI scores significantly improved in both groups after the operation. Between the subsidence and non-subsidence groups, there were significant differences in age, intervertebral distraction height, and HU value in both upper and lower vertebral body and endplate. The logistic regression analysis proved that the HU value of the lower vertebral body was an independent risk of TMC subsidence, the AUC was 0.866, and the most appropriate threshold of the HU value was 275 (sensitivity: 87.5%, specificity: 79.3%).
conclusionPreoperative cervical CT value is an independent correlative factor for early TMC subsidence after ACCF, and patients with a low CT value of the inferior vertebral body of the operative segment have a higher risk of TMC subsidence in the early postoperative period.
trial registrationThis study is undergoing retrospective registration.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.