Evidence map›Paper›PMID 35842582›Full record

ArticleBMC pregnancy and childbirth2022

Gestational weight gain mediates the effects of energy intake on birth weight among singleton pregnancies in the Japan Environment and Children's Study.

Marina Minami, Naw Awn J-P, Shuhei Noguchi, Masamitsu Eitoku, Sifa Marie Joelle Muchanga, Naomi Mitsuda, Kaori Komori, Kahoko Yasumitsu-Lovell, Nagamasa Maeda, Mikiya Fujieda and 2 more

Open access · goldAbstract read
In one paragraph

Article in BMC pregnancy and childbirth, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
3.0field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 18 citations in OpenAlex.

  1. Observational
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 1 institution in 1 country.

Marina MinamiDepartment of Environmental Medicine, Kochi Medical School, Kochi University, Nankoku, Kochi, 783-8505, Japan.
Naw Awn J-PDepartment of Environmental Medicine, Kochi Medical School, Kochi University, Nankoku, Kochi, 783-8505, Japan.
Shuhei NoguchiDepartment of Environmental Medicine, Kochi Medical School, Kochi University, Nankoku, Kochi, 783-8505, Japan.
Masamitsu EitokuDepartment of Environmental Medicine, Kochi Medical School, Kochi University, Nankoku, Kochi, 783-8505, Japan. meitoku@kochi-u.ac.jp.
Sifa Marie Joelle MuchangaDepartment of Environmental Medicine, Kochi Medical School, Kochi University, Nankoku, Kochi, 783-8505, Japan.
Naomi MitsudaDepartment of Environmental Medicine, Kochi Medical School, Kochi University, Nankoku, Kochi, 783-8505, Japan.
Kaori KomoriDepartment of Environmental Medicine, Kochi Medical School, Kochi University, Nankoku, Kochi, 783-8505, Japan.
Kahoko Yasumitsu-LovellDepartment of Environmental Medicine, Kochi Medical School, Kochi University, Nankoku, Kochi, 783-8505, Japan.
Nagamasa MaedaDepartment of Obstetrics and Gynecology, Kochi Medical School, Kochi University, Nankoku, Kochi, Japan.
Mikiya FujiedaDepartment of Pediatrics, Kochi Medical School, Kochi University, Nankoku, Kochi, Japan.
Narufumi SuganumaDepartment of Environmental Medicine, Kochi Medical School, Kochi University, Nankoku, Kochi, 783-8505, Japan.
Japan Environment and Children’s Study (JECS) Group
Kōchi University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundExtra energy intake is commonly recommended for pregnant women to support fetal growth. However, relevant data regarding variations in energy intake and expenditure, body mass index and gestational weight gain (GWG) are frequently not considered. This study aimed to investigate how energy intake during pregnancy and gestational weight gain (GWG) are associated with birth weight.

methodsEarly pregnant women were recruited into a Japanese nationwide prospective birth cohort study between 2011 and 2014. We analysed data of 89,817 mother-child pairs of live-born non-anomalous singletons after excluding births before 28 weeks or after 42 weeks. Energy intake during pregnancy was estimated from self-administered food frequency questionnaires (FFQ) and was stratified into low, medium, and high. Participants completed the FFQ in mid-pregnancy (mean 27.9 weeks) by recalling food consumption at the beginning of pregnancy. Effects of energy intake on birth weight and mediation by GWG were estimated using the Karlson-Holm-Breen method; the method separates the impact of confounding in the comparison of conditional and unconditional parameter estimates in nonlinear probability models. Relative risks and risk differences for abnormal birth size were calculated.

resultsMean daily energy intake, GWG, and birth weight were 1682.1 (533.6) kcal, 10.3 (4.0) kg, and 3032.3 (401.4) g, respectively. 6767 and 9010 women had small-for-gestational-age and large-for-gestational-age infants, respectively. Relative to low energy intake, moderate and high intakes increased adjusted birth weights by 13 g and 24 g, respectively: 58 and 69% of these effects, respectively, were mediated by GWG. Compared with the moderate energy intake group, the low energy intake group had seven more women per 1000 women with a small-for-gestational-age birth, whereas the high energy intake group had eight more women per 1000 women with a large-for-gestational-age birth.

conclusionGWG mediates the effect of energy intake on birth weight. All pregnant women should be given adequate nutritional guidance for optimal GWG and fetal growth.

Indexed as

Gestational Weight GainBirth WeightBody Mass IndexCohort StudiesEnergy IntakeFemaleHumansJapanPregnancyPregnancy OutcomeProspective StudiesWeight GainBirth weightEnergy intakeFetal developmentGestational weight gainPregnancySmall for gestational age

Identifiers

PMID35842582
PMCPMC9287949
OpenAlexW4285587555

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.