ArticleAging clinical and experimental research2022
Diet-induced inflammation is associated with sarcopenia and muscle strength in older adults who visit a frailty clinic.
Article in Aging clinical and experimental research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 3 of them syntheses that pooled it.
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Who cites it
8 citing papers in PubMed, 3 syntheses or guidelines pooled it, 9 citations in OpenAlex.
- The association of dietary inflammatory potential with skeletal muscle strength, mass, and sarcopenia: a meta-analysis.Frontiers in nutrition · 2023Pooled it
- The Association between Dietary Inflammatory Index and Aging Biomarkers/Conditions: A Systematic Review and Dose-response Meta-analysis.The journal of nutrition, health & aging · 2023Pooled it
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- Diet-induced inflammation and its association with sarcopenia in an Iranian population: a case-control study.Journal of health, population, and nutrition · 2025Article
- Systemic inflammation and changes in physical well-being in patients with breast cancer: a longitudinal study in community oncology settings.The oncologist · 2025Article
- Association of food group with the changes in sarcopenia parameters over 1 year in older outpatients in a frailty clinic.European geriatric medicine · 2024Article
- Epigenetic and inflammatory markers in older adults with cancer: A Young International Society of Geriatric Oncology narrative review.Journal of geriatric oncology · 2024Review
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Authors and funding
12 authors at 6 institutions in 1 country.
Funding
Abstract
backgroundDiet-induced inflammation may be associated with sarcopenia; however, few reports have examined this relationship.
aimTo examine the association between the dietary inflammatory index (DII) and sarcopenia in older adults who visited a frailty clinic in Japan.
methodsThis cross-sectional study used outpatient data from the Frailty Registry Study. The DII is an index of diet-induced inflammation, and a dietary assessment was performed using a brief self-administered diet history questionnaire to calculate the DII score. We classified DII scores by quartiles (Q1-Q4), and sarcopenia was diagnosed according to the Asian Working Group for Sarcopenia 2019 consensus. Logistic regression analyses for sarcopenia were performed. Age, sex, comorbidities, and physical activity were entered as confounding factors (Model 1) and Models 2, 3, and 4 with BMI, protein intake, and energy intake added to Model 1.
resultsWe included 304 patients in the analysis (mean age, 77.6 ± 6.3 years; female, 67.4%). The prevalence of sarcopenia was 14.5%. Logistic regression analyses showed that DII scores were significantly associated with sarcopenia in Model 1 and 2 (Model 1, reference: Q1, Q4: OR 3.10, P = 0.020; Model 2, Q4: OR 3.40, P = 0,022) but not in Model 3 and 4. DISCUSSION: Diet-induced inflammation is associated with a higher likelihood of sarcopenia; however, this association disappeared after confounding for protein and energy intake.
conclusionsThe results demonstrated that dietary protein and energy parameters were the main drivers for muscle health in medical patients.
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