Evidence map›Paper›PMID 35841423›Full record

ArticleArchives of gynecology and obstetrics2022

Study of association between different microRNA variants and the risk of idiopathic recurrent pregnancy loss.

Shayma Abd Ezat, Azheen Ismael Haji

Abstract read
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In one paragraph

Article in Archives of gynecology and obstetrics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
0.7field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 8 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Observational
  4. Article
  5. The effect of MicroRNAs variants on idiopathic recurrent pregnancy loss.Journal of assisted reproduction and genetics · 2023
    Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Shayma Abd EzatDepartment of Obstetrics and Gynecology, College of Medicine, Iraqi Board in Obstetrics/Gynecology, Hawler Medical University, Erbil, Kurdistan Region, 54612504, Iraq. shayma.abd@hmu.edu.krd.
Azheen Ismael HajiDepartment of Obstetrics and Gynecology, Maternity Teaching Hospital, Erbil, Kurdistan Region, Iraq.
Hawler Medical University · IQUniversity of Kurdistan Hewler · IQ

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimRecurrent pregnancy loss (RPL) is a common reproductive disorder among women and a major cause of infertility among them; however, the underlying causes of RPL remain unknown which have led to great difficulties and complications in the treatment. MicroRNAs (miRNA) have been shown to be a potential diagnosis tools in different reproductive disorders. This study aimed to investigate the association of four different miRNA variants with the risk of idiopathic RPL (iRPL).

methodsA total of 450 women including 225 patients and 225 controls were recruited in this study. DNA was extracted, and genotyped by PCR method. Haplotype analysis, as well as linkage disequilibrium between SNPs, was performed.

conclusionThis study suggested that rs4636297, rs41291957, and rs353292, but not rs531564 can play a risk factor role for iRLP.

Indexed as

Abortion, HabitualMicroRNAsCase-Control StudiesFemaleGenetic Predisposition to DiseaseGenotypeHumansPolymorphism, Single NucleotidePregnancyMicroRNAsFemale infertilityIdiopathic recurrent pregnancy lossmiRNAsReproductive disorder

Identifiers

PMID35841423
OpenAlexW4285588302

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.