Evidence map›Paper›PMID 35841056›Full record

ArticleTrials2022

Effects of robotic priming of bilateral arm training, mirror therapy, and impairment-oriented training on sensorimotor and daily functions in patients with chronic stroke: study protocol of a single-blind, randomized controlled trial.

Yi-Chen Lee, Yi-Chun Li, Keh-Chung Lin, Grace Yao, Ya-Ju Chang, Ya-Yun Lee, Chien-Ting Liu, Wan-Ling Hsu, Yi-Hsuan Wu, Ho-Ta Chu and 3 more

Registry-linked trialOpen access · goldAbstract readClinical Trial Protocol
PubMed Full text at PMC Publisher
In one paragraph

Article in Trials, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03773653 (Synergistic Bilateral Upper-Limb Stroke Rehabilitation Based on Robotic Priming Technique), which is not on this map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
0.8field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03773653 nacompletednot on this map

Synergistic Bilateral Upper-Limb Stroke Rehabilitation Based on Robotic Priming Technique

TypeinterventionalSponsorNational Taiwan University HospitalRan2018 to 2023Enrolled81ConditionsStroke RehabilitationArmsBMT to be combined with BAT, BMT to be combined with MT, BMT to be combined with IOT
3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 8 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 5 institutions in 1 country.

Yi-Chen LeeSchool of Occupational Therapy, College of Medicine, National Taiwan University, 17, F4, Xu Zhou Road, Taipei, Taiwan.
Yi-Chun LiSchool of Occupational Therapy, College of Medicine, National Taiwan University, 17, F4, Xu Zhou Road, Taipei, Taiwan.
Keh-Chung LinSchool of Occupational Therapy, College of Medicine, National Taiwan University, 17, F4, Xu Zhou Road, Taipei, Taiwan. kehchunglin@ntu.edu.tw.ORCID http://orcid.org/0000-0003-1110-8773
Grace YaoDepartment of Psychology, National Taiwan University, Taipei, Taiwan.
Ya-Ju ChangNeuroscience Research Center, Chang Gung Memorial Hospital, Taoyuan, Taiwan.
Ya-Yun LeeSchool and Graduate Institute of Physical Therapy, College of Medicine, National Taiwan University, Taipei, Taiwan.
Chien-Ting LiuDepartment of Rehabilitation, Taipei Tzu Chi Hospital, the Buddhist Tzu-Chi Medical Foundation, Taipei, Taiwan.
Wan-Ling HsuDepartment of Rehabilitation, Taipei Tzu Chi Hospital, the Buddhist Tzu-Chi Medical Foundation, Taipei, Taiwan.
Yi-Hsuan WuDivision of Occupational Therapy, Department of Physical Medicine and Rehabilitation, National Taiwan University Hospital, Taipei, Taiwan.
Ho-Ta ChuRehabilitation Department, Taipei Hospital, Ministry of Health and Welfare, New Taipei City, Taiwan.
Ting-Xuan LiuSchool of Occupational Therapy, College of Medicine, National Taiwan University, 17, F4, Xu Zhou Road, Taipei, Taiwan.
Yi-Ping YehSchool of Occupational Therapy, College of Medicine, National Taiwan University, 17, F4, Xu Zhou Road, Taipei, Taiwan.
Chieh ChangSchool of Occupational Therapy, College of Medicine, National Taiwan University, 17, F4, Xu Zhou Road, Taipei, Taiwan.
National Taiwan University · TWTaipei Tzu Chi Hospital · TWChang Gung University · TWMinistry of Health and Welfare · TWNational Taiwan University Hospital · TW

Funding

the Ministry of Science and Technology MOST 108-2314-B-002-165-MY3the National Health Research Institutes NHRI-EX109-10929PI
6 · The paper itself

Abstract

backgroundCombining robotic therapy (RT) with task-oriented therapy is an emerging strategy to facilitate motor relearning in stroke rehabilitation. This study protocol will compare novel rehabilitation regimens that use bilateral RT as a priming technique to augment two task-oriented therapies: mirror therapy (MT) and bilateral arm training (BAT) with a control intervention: RT combined with impairment-oriented training (IOT).

methodsThis single-blind, randomized, comparative efficacy study will involve 96 participants with chronic stroke. Participants will be randomized into bilateral RT+MT, bilateral RT+BAT, and bilateral RT+IOT groups and receive 18 intervention sessions (90 min/day, 3 d/week for 6 weeks). The outcomes will include the Fugl-Meyer Assessment, Stroke Impact Scale version 3.0, Medical Research Council scale, Revised Nottingham Sensory Assessment, ABILHAND Questionnaire, and accelerometer and will be assessed at baseline, after treatment, and at the 3-month follow-up. Analysis of covariance and the chi-square automatic interaction detector method will be used to examine the comparative efficacy and predictors of outcome, respectively, after bilateral RT+MT, bilateral RT+BAT, and bilateral RT+IOT. DISCUSSION: The findings are expected to contribute to the research and development of robotic devices, to update the evidence-based protocols in postacute stroke care programs, and to investigate the use of accelerometers for monitoring activity level in real-life situations, which may in turn promote home-based practice by the patients and their caregivers. Directions for further studies and empirical implications for clinical practice will be further discussed in upper-extremity rehabilitation after stroke.

trial registrationThis trial was registered December 12, 2018, at www. CLINICALTRIALS: gov ( NCT03773653 ).

Indexed as

Mirror Movement TherapyRoboticsStrokeStroke RehabilitationActivities of Daily LivingArmHumansRandomized Controlled Trials as TopicRecovery of FunctionSingle-Blind MethodTreatment OutcomeUpper ExtremityBilateral arm trainingBilateral motor primingImpairment-oriented trainingMirror therapyRandomized controlled trialStrokeUpper extremity rehabilitation

Identifiers

PMID35841056
PMCPMC9287972
OpenAlexW4285491668

What OpenQuestion holds

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LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.