Evidence map›Paper›PMID 35840998›Full record

ReviewBiomarker research2022

Roles of circRNAs in hematological malignancies.

Fahua Deng, Chengsi Zhang, Tingting Lu, Ezhong Joshua Liao, Hai Huang, Sixi Wei

Open access · goldAbstract readReview
In one paragraph

Review in Biomarker research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 14 citations in OpenAlex.

  1. DecipheringGenes · 2026
    Article
  2. Article
  3. Article
  4. Review
  5. Review
  6. Article
  7. Review
  8. [Molecular Mechanism of circVRK1 Regulating the Proliferation and Apoptosis of Acute Lymphoblastic Leukemia KOCL44 Cells by Targeting miR-4428].Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition · 2024
    Article
  9. Review
  10. Review
  11. Article
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Fahua DengDepartment of Clinical Biochemistry, School of Clinical Laboratory Science, Guizhou Medical University, Guiyang, 550004, Guizhou Province, China.
Chengsi ZhangDepartment of Clinical Biochemistry, School of Clinical Laboratory Science, Guizhou Medical University, Guiyang, 550004, Guizhou Province, China.
Tingting LuDepartment of Clinical Biochemistry, School of Clinical Laboratory Science, Guizhou Medical University, Guiyang, 550004, Guizhou Province, China.
Ezhong Joshua LiaoCenter for Clinical Laboratories, The Affiliated Hospital of Guizhou Medical University, Guiyang, 550004, Guizhou Province, China.
Hai HuangDepartment of Clinical Biochemistry, School of Clinical Laboratory Science, Guizhou Medical University, Guiyang, 550004, Guizhou Province, China. huanghai828@gmc.edu.cn.
Sixi WeiDepartment of Clinical Biochemistry, School of Clinical Laboratory Science, Guizhou Medical University, Guiyang, 550004, Guizhou Province, China. wsixi@gmc.edu.cn.
Affiliated Hospital of Guizhou Medical University · CNGuiyang Medical University · CN

Funding

Hai Huang 5610Sixi Wei 81960031
6 · The paper itself

Abstract

As one of the leading causes of death, hematologic malignancies are associated with an ever-increasing incidence, and drug resistance and relapse of patients after treatment represent clinical challenges. Therefore, there are pressing demands to uncover biomarkers to indicate the development, progression, and therapeutic targets for hematologic malignancies. Circular RNAs (circRNAs) are covalently closed circular-single-stranded RNAs whose biosynthesis is regulated by various factors and is widely-expressed and evolutionarily conserved in many organisms and expressed in a tissue-/cell-specific manner. Recent reports have indicated that circRNAs plays an essential role in the progression of hematological malignancies. However, circRNAs are difficult to detect with low abundance using conventional techniques. We need to learn more information about their features to develop new detection methods. Herein, we sought to retrospect the current knowledge about the characteristics of circRNAs and summarized research on circRNAs in hematological malignancies to explore a potential direction.

Indexed as

circRNA functionscircRNAsHematological malignanciesNon-coding RNAs

Identifiers

PMID35840998
PMCPMC9284813
OpenAlexW4285592459

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.