Evidence map›Paper›PMID 35840929›Full record

ArticleBMC infectious diseases2022

Health care consequences of hospitalization with Clostrioides difficile infection: a propensity score matching study.

Bruce E Hirsch, Myia S Williams, Dimitre G Stefanov, Martin L Lesser, Karalyn Pappas, Thomas Iglio, Craig Gordon, Renee Pekmezaris

Abstract read
In one paragraph

Article in BMC infectious diseases, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Trial
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Bruce E HirschDivision of Infectious Disease, Northwell Health, Manhasset, NY, 11030, USA.
Myia S WilliamsDonald and Barbara Zucker School of Medicine at Hofstra/Northwell, Hempstead, NY, USA. mwilliam26@northwell.edu.
Dimitre G StefanovBiostatistics Unit, The Feinstein Institutes for Medical Research, Manhasset, NY, 11030, USA.
Martin L LesserDonald and Barbara Zucker School of Medicine at Hofstra/Northwell, Hempstead, NY, USA.
Karalyn PappasBiostatistics Unit, The Feinstein Institutes for Medical Research, Manhasset, NY, 11030, USA.
Thomas IglioDepartment of Planning, Northwell Health, New Hyde Park, NY, 11042, USA.
Craig GordonDepartment of Planning, Northwell Health, New Hyde Park, NY, 11042, USA.
Renee PekmezarisDonald and Barbara Zucker School of Medicine at Hofstra/Northwell, Hempstead, NY, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundClostridiodies difficile infection (CDI) has been characterized by the Center for Disease Control and Prevention (CDC) as an urgent public health threat and a major concern in hospital, outpatient and extended-care facilities worldwide.

methodsA retrospective cohort study of patients aged ≥ 18 hospitalized with CDI in New York State (NYS) between January 1, 2014-December 31, 2016. Data were extracted from NY Statewide Planning and Research Cooperative (SPARCS) and propensity score matching was performed to achieve comparability of the CDI (exposure) and non-CDI (non-exposure) groups. Of the 3,714,486 hospitalizations, 28,874 incidence CDI cases were successfully matched to 28,874 non-exposures.

resultsThe matched pairs comparison demonstrated that CDI cases were more likely to be readmitted to the hospital at 30 (28.26% vs. 19.46%), 60 (37.65% vs. 26.02%), 90 (42.93% vs. 30.43) and 120 days (46.47% vs. 33.74), had greater mortality rates at 7 (3.68% vs. 2.0%) and 180 days (20.54% vs. 11.96%), with significant increases in length of stay and total hospital charges (p < .001, respectively).

conclusionsCDI is associated with a large burden on patients and health care systems, significantly increasing hospital utilization, costs and mortality.

Indexed as

Clostridioides difficileClostridium InfectionsCross InfectionHealth Care CostsHospitalizationHumansLength of StayPropensity ScoreRetrospective StudiesClostridioides difficile infectionHospitalizationsMortalitySPARCS

Identifiers

PMID35840929
PMCPMC9287953

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.