Evidence map›Paper›PMID 35840919›Full record

ArticleBMC infectious diseases2022

A case report of Klebsiella aerogenes-caused lumbar spine infection identified by metagenome next-generation sequencing.

Huajie Gu, Qingqing Cai, Xiaoyong Dai, Huanhuan Wang, Wenying Xu, Xuejie Cao, Youwen Ye

Open access · goldAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC infectious diseases, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 9 citations in OpenAlex.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Huajie GuDepartment of Emergency Intensive Care Unit, Yangpu Hospital, School of Medicine, Tongji University, 450 Tengyue Road, Shanghai, China.
Qingqing CaiGenoxor Medical Science and Technology Inc., Shanghai, China.
Xiaoyong DaiDepartment of Emergency Intensive Care Unit, Yangpu Hospital, School of Medicine, Tongji University, 450 Tengyue Road, Shanghai, China.
Huanhuan WangDepartment of Emergency Intensive Care Unit, Yangpu Hospital, School of Medicine, Tongji University, 450 Tengyue Road, Shanghai, China.
Wenying XuDepartment of Radiology, Yangpu Hospital, School of Medicine, Tongji University, Shanghai, China.
Xuejie CaoGenoxor Medical Science and Technology Inc., Shanghai, China.
Youwen YeDepartment of Emergency Intensive Care Unit, Yangpu Hospital, School of Medicine, Tongji University, 450 Tengyue Road, Shanghai, China. ye.bamboo@hotmail.com.ORCID http://orcid.org/0000-0001-6765-3207
Yangpu Hospital of Tongji University · CN

Funding

Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences and Peking Union Medical College Z-2017-24-2026Science and Technology Commission of Shanghai Municipality 201840314
6 · The paper itself

Abstract

backgroundThe early clinical diagnosis of spinal infections in elderly patients with recessive or atypical symptoms is difficult. Klebsiella aerogenes is a common opportunistic bacterium that can infect the respiratory tract, urinary tract, and even the central nervous system. However, whether it can infect the lumbar spine has not been previously described. CASE PRESENTATION: In this paper, we report the case of a 69-year-old female patient with osteoporosis who was initially diagnosed with hemolytic anemia. Later, she was diagnosed with K. aerogenes infection of the lumbar spine based on imaging combined with blood culture and metagenome next-generation sequencing (mNGS) detection. After precise medication, the lumbar degeneration was improved.

conclusionsBacterial infection should therefore be considered in cases of lumbar degenerative disease in middle-aged and elderly patients.

Indexed as

Enterobacter aerogenesKlebsiella InfectionsAgedFemaleHigh-Throughput Nucleotide SequencingHumansLumbar VertebraeMetagenomeMiddle AgedBlood cultureCase reportKlebsiella aerogenesMetagenome next-generation sequencingSpinal infection

Identifiers

PMID35840919
PMCPMC9288078
OpenAlexW4285589593

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.