Evidence map›Paper›PMID 35840826›Full record

ArticleIrish journal of medical science2023

MRA-detected intracranial atherosclerotic disease in patients with TIA and minor stroke.

Philip J Dempsey, Mark C Murphy, Michael Marnane, Sean Murphy, Eoin C Kavanagh

Open access · hybridAbstract read
In one paragraph

Article in Irish journal of medical science, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.2field-weighted citation impact, top 51% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Philip J DempseyDepartment of Radiology, Mater Misericordiae University Hospital, Eccles Street, Dublin 7, Ireland. philipjdempsey@gmail.com.ORCID http://orcid.org/0000-0001-5848-9003
Mark C MurphyDepartment of Radiology, Mater Misericordiae University Hospital, Eccles Street, Dublin 7, Ireland.
Michael MarnaneStroke Department, Dublin Neurovascular Institute, Mater Misericordiae University Hospital, Eccles Street, Dublin 7, Ireland.
Sean MurphyStroke Department, Dublin Neurovascular Institute, Mater Misericordiae University Hospital, Eccles Street, Dublin 7, Ireland.
Eoin C KavanaghDepartment of Radiology, Mater Misericordiae University Hospital, Eccles Street, Dublin 7, Ireland.
Mater Misericordiae University Hospital · IE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesPatients with TIA and minor stroke commonly undergo CT and CTA in the emergency department with subsequent MRI with MRA for further workup. The purpose of this study was to review outpatient MRIs for TIA/stroke patients to assess the additional benefit, if any, of the MRA sequence in the detection of intracranial atherosclerotic disease in patients for whom CTA had already been performed.

methodsThe radiology reports of outpatient MRIs of the brain for TIA/minor stroke patients were retrospectively reviewed via the hospital PACS system. Following this, the imaging report from the patient's initial presentation to the emergency department was reviewed. This index imaging and subsequent MRI were compared to assess the incidence of new vascular findings detected on the MRA sequence in patients for whom CTA had already been performed. Where new lesions had been identified at follow-up, the imaging was retroactively reviewed to assess if they were present on the index imaging.

resultsTwo hundred seven consecutive patients were reviewed. Significant (> 50%) intracranial atherosclerotic disease was present on MRA in 18 patients (8.7%). This was a new finding in 11 patients. Five had initial CTA where the atherosclerosis was not detected. All 5 of these cases were located in the posterior cerebral arteries. Incidental aneurysms were seen in 14 (6.7%); 12 were a new finding at time of MRI.

conclusionThe MRA sequence provides additional value by increasing the detection of clinically important intracranial atherosclerotic disease which may inform management in patients with minor stroke and TIA.

Indexed as

AtherosclerosisIntracranial ArteriosclerosisIschemic Attack, TransientStrokeHumansMagnetic Resonance AngiographyRetrospective StudiesTomography, X-Ray ComputedIntracranial atherosclerotic diseaseMRAStrokeTIA

Identifiers

PMID35840826
PMCPMC10250431
OpenAlexW4285592024

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.