Evidence map›Paper›PMID 35840710›Full record

ArticleJournal of perinatology : official journal of the California Perinatal Association2022

A comparison of bacterial colonization between nasogastric and orogastric enteral feeding tubes in infants in the neonatal intensive care unit.

Kannikar Vongbhavit, Lauren K Salinero, Karen M Kalanetra, Chad Masarweh, Alice Yu, Diana H Taft, David A Mills, Mark A Underwood

Open access · hybridAbstract read
In one paragraph

Article in Journal of perinatology : official journal of the California Perinatal Association, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.7field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. The neonate respiratory microbiome.Acta physiologica (Oxford, England) · 2025
    Review
  6. Article
  7. A Scoping Review of the Oral Microbiome in Preterm Infants.American journal of perinatology · 2024
    Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Kannikar VongbhavitDepartment of Pediatrics, HRH Princess Maha Chakri Sirindhorn Medical Center, Srinakharinwirot University, Nakornayok, Thailand.
Lauren K SalineroDepartment of Food Science and Technology, University of California Davis, Davis, CA, USA.
Karen M KalanetraDepartment of Food Science and Technology, University of California Davis, Davis, CA, USA.
Chad MasarwehDepartment of Food Science and Technology, University of California Davis, Davis, CA, USA.
Alice YuDepartment of Food Science and Technology, University of California Davis, Davis, CA, USA.
Diana H TaftDepartment of Food Science and Technology, University of California Davis, Davis, CA, USA.
David A MillsDepartment of Food Science and Technology, University of California Davis, Davis, CA, USA.
Mark A UnderwoodDivision of Neonatology, Department of Pediatrics, University of California Davis, Sacramento, CA, USA. munderwood@ucdavis.edu.ORCID http://orcid.org/0000-0001-7453-5022
University of California, Davis · USSrinakharinwirot University · THUniversity of California System · US

Funding

Activation of probiotic bifidobacteria by milk glyansR01AT008759 · NCCIH · UNIVERSITY OF CALIFORNIA AT DAVIS · PI GERMAN, BRUCE, LEBRILLA, CARLITO B · 2014 to 2018
$4.2M
Effects of Bifidobacterium Dominance on the Infant MicrobiomeF32HD093185 · NICHD · UNIVERSITY OF CALIFORNIA AT DAVIS · PI TAFT, DIANA HAZARD · 2017 to 2020
$218k
NCCIH NIH HHS AT008759NCCIH NIH HHS R01 AT008759NICHD NIH HHS F32 HD093185NICHD NIH HHS F32HD093185
6 · The paper itself

Abstract

objectiveFeeding tubes harbor microbial contaminants; studies to date have not explored differences between orogastric (OG) and nasogastric (NG) tube biofilms. We sought to extend a previous analysis by comparing bacterial colonization by location (OG v NG) and by evaluating clinical factors that may affect tube bacterial populations. STUDY

designThe pharyngeal segments of 41 infant feeding tubes (14 OG and 27 NG) from 41 infants were analyzed by next generation 16 S rRNA sequencing on the MiSeq platform.

resultsAt the phylum level, Proteobacteria had the highest relative abundance of both OG and NG tubes. At the genus/species level, nine taxa differed significantly between OG and NG tubes. Alpha and beta diversity analyses showed significant differences between OG and NG tubes with relatively little contribution from clinical factors.

conclusionThe route of feeding tube insertion (oral vs nasal) had a greater impact on bacterial colonization than the assessed clinical factors.

Indexed as

Enteral NutritionIntensive Care Units, NeonatalBacteriaHumansInfantInfant, NewbornIntubation, GastrointestinalNose

Identifiers

PMID35840710
PMCPMC9616717
OpenAlexW4285491681

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.