ArticleScientific reports2022
Progression detection capabilities of circumpapillary and macular vessel density in advanced glaucomatous eyes.
Article in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed.
- Nonaxonal content of the circumpapillary retinal nerve fiber layer in experimental glaucoma.Optometry and vision science : official publication of the American Academy of Optometry · 2026Article
- Glaucoma Progression Detection Time Using OCT and OCTA in African and European Descendants.American journal of ophthalmology · 2026Article
- Multimodal AI-based modeling of glaucoma progression: a 3PM-guided approach integrating structural, functional, and vascular patterns.The EPMA journal · 2025Article
- Long-term variability of retinal nerve fibre layer thickness measurement in patients with glaucoma of African and European descents.The British journal of ophthalmology · 2024Article
- Detection and agreement of event-based OCT and OCTA analysis for glaucoma progression.Eye (London, England) · 2024Article
- Current Status and Future Perspectives of Optic Nerve Imaging in Glaucoma.Journal of clinical medicine · 2024Review
- Comparison of the Circumpapillary Structure-Function and Vasculature-Function Relationships at Different Glaucoma Stages Using Longitudinal Data.Investigative ophthalmology & visual science · 2024Article
- Clinical Factors Associated With Long-Term OCT Variability in Glaucoma.American journal of ophthalmology · 2023Article
- Retinal Oxygen Extraction in Patients with Primary Open-Angle Glaucoma.International journal of molecular sciences · 2022Article
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3 authors.
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Abstract
This study investigated the progression detection capabilities of circumpapillary and macular vessel density (cpVD and mVD) in advanced primary open angle glaucoma (POAG) eyes using the rates of change in VD (trend-based analysis) and variability limits derived from healthy eyes. (event-based analysis) This study included 75 POAG eyes [visual field (VF) mean deviation < - 10 decibels, mean follow-up; 2.3 years] and 33 healthy eyes. Of 75 POAG eyes, 17 (22.7 %) and 58 eyes (77.3 %) were classified into the VF progression and stable groups, respectively. The VF progression group showed significantly faster VD loss than the stable group. (cpVD; - 1.76 vs. - 0.84 %/year, mVD; - 1.10 vs. - 0.47 %/year, P < 0.05) However, the rates of change in circumpapillary retinal nerve fiber layer and macular ganglion cell complex thickness were similar between the groups. (cpRNFLT; - 0.67 vs. - 0.53 [Formula: see text]m/year, GCCT; - 0.48 vs. - 0.12 [Formula: see text]m/year, P > 0.05) Event-based analysis showed stronger agreement between VD and VF progression (cpVD; kappa value (k) = 0.630, mVD; k = 0.667, P < 0.05) than that between structure and VF progression. (cpRNFLT; k = 0.111, GCCT; k = 0.194, P > 0.05). In conclusion, VD loss showed better progression detection capabilities than structural loss in advanced POAG eyes. Detection of cpVD and mVD loss may be useful for detecting progression in the advanced stages of POAG to complement other reference standard strategies.
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