Trial reportESC heart failure2022
Peak O
Trial report in ESC heart failure, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02078947 (Optimizing Exercise Training in Prevention and Treatment of Diastolic Heart Failure- Clinical Study), which is not on this map. Cited by 11 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Optimizing Exercise Training in Prevention and Treatment of Diastolic Heart Failure- Clinical Study
Who cites it
11 citing papers in PubMed, 2 syntheses or guidelines pooled it, 16 citations in OpenAlex.
- Impact of exercise training on exercise tolerance, cardiac function and quality of life in individuals with heart failure and preserved ejection fraction: a systematic review and meta-analysis.BMC cardiovascular disorders · 2025Pooled it
- Brazilian Guideline for Exercise Test in the Adult Population - 2024.Arquivos brasileiros de cardiologia · 2024Guideline
- Training-induced change of diastolic function in heart failure with preserved ejection fraction.ESC heart failure · 2025Trial
- Combined endurance and resistance exercise training in heart failure with preserved ejection fraction: a randomized controlled trial.Nature medicine · 2025Trial
- Peak OESC heart failure · 2022Trial
- Cardiopulmonary Exercise Testing and HFpEF: Diagnostic and Therapeutic Perspectives.Healthcare (Basel, Switzerland) · 2025Review
- Movement behaviors and cardiorespiratory fitness - a cross-sectional compositional data analysis among German adults.BMC sports science, medicine & rehabilitation · 2025Article
- Advancing Cardiac Amyloidosis Care Through Insights from Cardiopulmonary Exercise Testing.Journal of clinical medicine · 2024Review
- Novel techniques for quantifying oxygen pulse curve characteristics during cardiopulmonary exercise testing in tetralogy of fallot.International journal of cardiology. Congenital heart disease · 2024Article
- Exercise Intolerance Is Associated with Cardiovascular Dysfunction in Long COVID-19 Syndrome.Journal of clinical medicine · 2024Article
- A year in heart failure: updates of clinical and preclinical findings.ESC heart failure · 2023Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
25 authors at 8 institutions in 5 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimsExercise training (ET) has been consistently shown to increase peak oxygen consumption (V̇O METHODS AND
resultsThis was a secondary analysis of the OptimEx-Clin (Optimizing Exercise Training in Prevention and Treatment of Diastolic Heart Failure, NCT02078947) trial, including all 158 patients with complete baseline and 3 month cardiopulmonary exercise testing measurements (106 ET, 52 CON). Change in peak V̇O
conclusionsIn patients with HFpEF, the easily measurable peak O
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.