Evidence map›Paper›PMID 35840527›Full record

ArticleTrends in immunology2022

De-stressing plaques attenuates atherosclerosis progression.

Felix Sebastian Nettersheim, Klaus Ley

Open access · greenAbstract readComment
PubMed Full text at PMC Publisher
In one paragraph

Article in Trends in immunology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.3field-weighted citation impact, top 50% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 2 countries.

Felix Sebastian NettersheimLa Jolla Institute for Immunology, La Jolla, CA, USA; Department of Cardiology, Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany.
Klaus LeyLa Jolla Institute for Immunology, La Jolla, CA, USA; Department of Bioengineering, University of California, San Diego, San Diego, CA, USA; Immunology Center of Georgia (IMMCG), Augusta University Immunology Center of Georgia, 1410 Laney Walker Blvd, CN4315 Augusta, GA 30912, USA. Electronic address: klaus@lji.org.
La Jolla Institute for Immunology · USUniversity Hospital Cologne · DE

Funding

Vascular macrophages and T cells in atherosclerosisR35HL145241 · NHLBI · LA JOLLA INSTITUTE FOR IMMUNOLOGY · PI LEY, KLAUS F. · 2019 to 2025
$5.9M
Myeloid cell interactions with T cells in atherosclerosisR01HL115232 · NHLBI · LA JOLLA INSTITUTE FOR IMMUNOLOGY · PI LEY, KLAUS F. · 2012 to 2018
$3.2M
NHLBI NIH HHS R01 HL115232NHLBI NIH HHS R35 HL145241
6 · The paper itself

Abstract

Atherogenesis is accompanied by formation of immune cell aggregates, so-called artery tertiary lymphoid organs (ATLOs), in the outermost layer of diseased arteries. In a recent study, Mohanta, Habenicht, and colleagues revealed that there are distinct interactions between ATLOs and the autonomous nervous system, which are critically implicated in atherosclerosis progression.

Indexed as

AtherosclerosisHumansatherosclerosisATLOautonomous nervous systemsynapse

Identifiers

PMID35840527
PMCPMC10108377
OpenAlexW4285045514

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.