Evidence map›Paper›PMID 35839777›Full record

ArticleCancer cell2022

Immune suppression in the tumor-draining lymph node corresponds with distant disease recurrence in patients with melanoma.

Anneloes van Krimpen, Vivian I V Gerretsen, Evalyn E A P Mulder, Mandy van Gulijk, Thierry P P van den Bosch, Jan von der Thüsen, Dirk J Grünhagen, Cornelis Verhoef, Dana Mustafa, Joachim G Aerts and 2 more

Abstract readLetter
PubMed Publisher
In one paragraph

Article in Cancer cell, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Review
  6. Melanoma evolution in the lymph node shapes systemic outcomes.bioRxiv : the preprint server for biology · 2026
    Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Review
  12. Article
  13. Article
  14. Dynamic evolution and antitumor mechanisms of CXCR6Journal of translational medicine · 2025
    Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

12 authors.

Anneloes van KrimpenDepartment of Pulmonary Medicine, Erasmus Medical Centre, Rotterdam, the Netherlands; Erasmus MC Cancer Institute, Erasmus Medical Center, Rotterdam, the Netherlands.
Vivian I V GerretsenDepartment of Pulmonary Medicine, Erasmus Medical Centre, Rotterdam, the Netherlands; Erasmus MC Cancer Institute, Erasmus Medical Center, Rotterdam, the Netherlands; Laboratory of Immunoregulation and Mucosal Immunology, Vlaams Instituut voor Biotechnologie (VIB), Inflammation Research Center, Ghent, Belgium.
Evalyn E A P MulderErasmus MC Cancer Institute, Erasmus Medical Center, Rotterdam, the Netherlands; Department of Surgical Oncology, Erasmus Medical Center, Rotterdam, the Netherlands.
Mandy van GulijkDepartment of Pulmonary Medicine, Erasmus Medical Centre, Rotterdam, the Netherlands; Erasmus MC Cancer Institute, Erasmus Medical Center, Rotterdam, the Netherlands.
Thierry P P van den BoschDepartment of Pathology, Erasmus Medical Center, Rotterdam, the Netherlands.
Jan von der ThüsenDepartment of Pathology, Erasmus Medical Center, Rotterdam, the Netherlands.
Dirk J GrünhagenErasmus MC Cancer Institute, Erasmus Medical Center, Rotterdam, the Netherlands; Department of Surgical Oncology, Erasmus Medical Center, Rotterdam, the Netherlands.
Cornelis VerhoefErasmus MC Cancer Institute, Erasmus Medical Center, Rotterdam, the Netherlands; Department of Surgical Oncology, Erasmus Medical Center, Rotterdam, the Netherlands.
Dana MustafaTumor Immuno-Pathology Laboratory, Department of Pathology, Erasmus Medical Center, Rotterdam, the Netherlands.
Joachim G AertsDepartment of Pulmonary Medicine, Erasmus Medical Centre, Rotterdam, the Netherlands; Erasmus MC Cancer Institute, Erasmus Medical Center, Rotterdam, the Netherlands. Electronic address: j.aerts@erasmusmc.nl.
Ralph StadhoudersDepartment of Pulmonary Medicine, Erasmus Medical Centre, Rotterdam, the Netherlands; Department of Cell Biology, Erasmus Medical Center, Rotterdam, the Netherlands.
Floris DammeijerDepartment of Pulmonary Medicine, Erasmus Medical Centre, Rotterdam, the Netherlands; Erasmus MC Cancer Institute, Erasmus Medical Center, Rotterdam, the Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

MelanomaSkin NeoplasmsHumansLymph NodesNeoplasm Recurrence, LocalRetrospective Studies

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.