Evidence map›Paper›PMID 35839512›Full record

ReviewTransboundary and emerging diseases2022

Leishmania tarentolae: A new frontier in the epidemiology and control of the leishmaniases.

Jairo Alfonso Mendoza-Roldan, Jan Votýpka, Claudio Bandi, Sara Epis, David Modrý, Lucie Tichá, Petr Volf, Domenico Otranto

Open access · hybridAbstract readReview
In one paragraph

Review in Transboundary and emerging diseases, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
7.2field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 36 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Trypanothione reductase overexpression increases the infectivity ofFrontiers in cellular and infection microbiology · 2026
    Article
  6. Beyond reptiles: the fire salamander as a potential host forInternational journal for parasitology. Parasites and wildlife · 2025
    Article
  7. Article
  8. Epidemiological dynamics ofMicrobial genomics · 2025
    Article
  9. UnveilingInternational journal for parasitology. Parasites and wildlife · 2025
    Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Sand Fly Fauna and Prevalence ofTransboundary and emerging diseases · 2025
    Article
  15. Article
  16. Article
  17. Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 3 countries.

Jairo Alfonso Mendoza-RoldanDepartment of Veterinary Medicine, University of Bari, Valenzano, Italy.
Jan VotýpkaDepartment of Parasitology, Faculty of Science, Charles University, Prague, Czech Republic.
Claudio BandiDepartment of Biosciences and Pediatric CRC "Romeo ed Enrica Invernizzi", University of Milan, Milan, Italy.
Sara EpisDepartment of Biosciences and Pediatric CRC "Romeo ed Enrica Invernizzi", University of Milan, Milan, Italy.
David ModrýBiology Centre, Institute of Parasitology, Czech Academy of Sciences, České Budějovice, Czech Republic.
Lucie TicháDepartment of Parasitology, Faculty of Science, Charles University, Prague, Czech Republic.
Petr VolfDepartment of Parasitology, Faculty of Science, Charles University, Prague, Czech Republic.
Domenico OtrantoDepartment of Veterinary Medicine, University of Bari, Valenzano, Italy.
Charles University · CZUniversity of Bari Aldo Moro · ITInstitute of Parasitology · CZIstituto Nazionale Genetica Molecolare · ITUniversity of Milan · IT

Funding

Czech Ministry of Education ERD funds CZ.02.1.01/0.0/0.0/16_019/0000759Fondazione "Romeo ed Enrica Invernizzi" CCE_FON17_CCP_SEPISFondazione "Romeo ed Enrica Invernizzi" LIB_VT21CBANDGrant Agency of Charles University GAUK 180220Research For Innovation - REFIN, Puglia, Italy 259045B0
6 · The paper itself

Abstract

Leishmaniasis (or the leishmaniases), classified as a neglected tropical parasitic disease, is found in parts of the tropics, subtropics and southern Europe. Leishmania parasites are transmitted by the bite of phlebotomine sand flies and million cases of human infection occur annually. Leishmania tarentolae has been historically considered a non-pathogenic protozoan of reptiles, which has been studied mainly for its potential biotechnological applications. However, some strains of L. tarentolae appear to be transiently infective to mammals. In areas where leishmaniasis is endemic, recent molecular diagnostics and serological positivity to L. tarentolae in humans and dogs have spurred interest in the interactions between these mammalian hosts, reptiles and Leishmania infantum, the main aetiologic agent of human and canine leishmaniasis. In this review, we discuss the systematics and biology of L. tarentolae in the insect vectors and the vertebrate hosts and address questions about evolution of reptilian leishmaniae. Furthermore, we discuss the possible usefulness of L. tarentolae for new vaccination strategies.

Indexed as

Dog DiseasesLeishmania infantumLeishmaniasisPsychodidaeAnimalsDogsEuropeHumansInsect VectorsMammalsLeishmania infantumleishmaniasis/leishmaniasesLeishmania tarentolaeSauroleishmaniaSergentomyiavaccine

Identifiers

PMID35839512
PMCPMC9804434
OpenAlexW4285589334

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.